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Description: Synthetic thermostable RNase inhibitor for single-cell RNA-sequencing (scRNAseq)
Biological Activity for SEQURNA
SEQURNA is a synthetic thermostable RNase inhibitor for single-cell RNA-sequencing (scRNAseq), yielding single-cell libraries of equal or superior quality compared to ubiquitously used protein-based recombinant RNase inhibitors (RRIs).
SEQURNA provides additional unique improvements in reproducibility and throughput, enables new experimental workflows including retained RNase inhibition throughout heat cycles, and can reduce the need for dry-ice transports.
SEQURNA is robust to various harsh treatments, such as pH changes, heating, freeze-thaw and vortexing.SEQURNA is compatible with Tn5 tagmentation and can replace RRI in Smart-seq3 express, extending the workable time-window of scRNAseq workflows. SEQURNA also works flawlessly with difficult RNase-rich cells.
Please refer to this protocol for further information on how to use this product.
Licensing Information
Sold under licensing from Genovis AB including use of the SEQURNA trademark.
Technical Data for SEQURNA
| Storage | Store at RT |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SEQURNA
| Solubility | Soluble in Aqueous solution (supplied at a concentration of 50 mass units/µL) |
Product Datasheets for SEQURNA
References for SEQURNA
References are publications that support the biological activity of the product.
Noble et al (2024) Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq. Nat.Comm. 15 PMID: 39333520
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Citations for SEQURNA
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