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Other Hydrolases

Inhibitors
Cat. No. Product Name / Activity
5402 6bK
Insulin degrading enzyme (IDE) inhibitor
5862 ARN 14686
Potent N-acylethanolamine acid amidase inhibitor; NAAA activity-based protein profiling (ABPP) probe
5861 ARN 726
Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe
0476 2,4-Diamino-6-hydroxypyrimidine
GTP cyclohydrolase I (GCH1) inhibitor
0478 Flurofamide
Urease inhibitor
4327 JW 480
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)
5844 JZP 430
Potent and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
5865 KLH 45
Potent DDHD2 inhibitor
6510 LNT 1
Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
6691 LP 922056
Notum inhibitor; activates Wnt signaling
5345 ML 348
Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor
5344 ML 349
Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor
6370 Nor NOHA monoacetate
Arginase inhibitor
7224 Oseltamivir phosphate
Influenza virus neuraminidase inhibitor; antiviral prodrug
5124 PD 404182
DDAH1 inhibitor; also KDO 8-P inhibitor
3384 (Z)-Pugnac
O-GlcNAcase and β-hexosaminidase inhibitor
6522 TH 1217
Potent dCTP pyrophosphatase 1 inhibitor
6534 TH 5427 hydrochloride
Potent NUDT5 inhibitor
4390 Thiamet G
Potent O-GlcNAcase inhibitor
5918 TPPU
Potent soluble epoxide hydrolase inhibitor; orally bioavailable and brain penetrant
5259 WWL 113
Ces3 and Ces1f inhibitor
5317 WWL 123
α/β-hydrolase domain 6 (ABHD6) inhibitor; antiepileptic
3252 WWL 70
Potent ABHD6 inhibitor

Activators
Cat. No. Product Name / Activity
3611 Lys-γ3-MSH
Activator of Hormone-sensitive lipase

Other
Cat. No. Product Name / Activity
6391 CD38 inhibitor 78c
Potent CD38 inhibitor; active in vivo
6903 DPTIP
Potent and selective N-SMase2 inhibitor; brain penetrant
6757 t-TUCB
Potent soluble epoxide hydrolase (sEH) Inhibitor; anti-inflammatory and antinociceptive