Cardiomyocyte Stem Cells
Induced pluripotent stem cells (iPS cells or iPSCs) can be reprogrammed into human cardiomyocyte-like cells, with the aim of being used to repair damaged tissue caused by myocardial infarction to support heart regeneration. In vivo studies have generated promising results showing proof of principle for regenerative stem cell therapy.
| Cat. No. | Product Name / Activity |
|---|---|
| 3084 | Anacardic acid |
| Promotes cardiomyocyte differentiation from mESCs; also histone acetyltransferase (HAT) inhibitor | |
| 3842 | 5-Azacytidine |
| DNA methyltransferase inhibitor; induces differentiation of MSCs into cardiomyocytes | |
| 3093 | Dorsomorphin dihydrochloride |
| Promotes cardiomyocyte differentiation in mouse ESCs; BMP type I receptor inhibitor | |
| 1041 | 1-EBIO |
| KCa activator; promotes ESC differentiation into cardiomyocytes | |
| 4439 | ISX 9 |
| Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation | |
| 5068 | ITD 1 |
| Selective inhibitor of TGF-beta signaling; induces cardiomyocyte differentiation in ESCs | |
| 3533 | IWP 2 |
| Promotes promotes cardiomyocyte differentiation from hPSCs; PORCN inhibitor | |
| 5214 | IWP 4 |
| Potent inhibitor of Wnt/β-catenin signaling; induces cardiomyocyte differentiation of human ESCs and iPSCs | |
| 6976 | JNJ 10198409 |
| Can be used conversion of fibroblasts to cardiomyocytes in combination with other small molecules | |
| 4731 | KY 02111 |
| Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes | |
| 7419 | Kyoto Probe-1 |
| Fluorescent probe that selectively identifies undifferentiated iPS/ES cells | |
| 4287 | Poly(I:C) |
| Accelerates maturation of hPSC-derived cardiomyocytes; synthetic double-stranded RNA (dsRNA) | |
| 6577 | Pyridone 6 |
| Promotes cardiac differentiation; potent pan-JAK inhibitor | |
| 3304 | SU 16f |
| Component of 9C cocktail for conversion of fibroblasts to cardiomyocytes; potent and selective PDGFRβ inhibitor | |
| 7690 | T 112 New |
| Promotes maturation of hiPSC-derived cardiomyocytes; estrogen-related receptor γ agonist | |
| 6666 | T3 |
| Promotes maturation of hPSC-derived cardiomyocytes; thyroid hormone. | |
| 5148 | Wnt-C59 |
| Wnt signaling inhibitor; induces differentiation of iPSCs to cardiomyocytes | |
| 3748 | XAV 939 |
| Promotes cardiomyogenesis; potent tankyrase inhibitor | |
| 2293 | Zebularine |
| DNA methyltransferase inhibitor; induces cardiomyocyte differentiation in MSCs |
Literature for Cardiomyocyte Stem Cells
Tocris offers the following scientific literature for Cardiomyocyte Stem Cells to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Research Product Guide
A collection of over 750 products for cancer research, the guide includes research tools for the study of:
- Cancer Metabolism
- Epigenetics in Cancer
- Receptor Signaling
- Cell Cycle and DNA Damage Repair
- Angiogenesis
- Invasion and Metastasis
Stem Cell Research Product Guide
This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:
- Self-renewal and Maintenance
- Differentiation
- Reprogramming
- Organoid Generation
- GMP and Ancillary Material Grade Products
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem Cell Workflow Poster
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.
Stem Cells Poster
Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.
Our Cancer Research Guide highlights over 750 products for cancer research.
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Our guide highlights the use of small molecules in stem cell research and cell therapy and lists relevant products.
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Our Stem Cells review gives an overview of the use of small molecules in the control of stem cell growth & differentiation and somatic cell reprogramming.
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Developed in-house, this poster summarizes how small molecules have been used in protocols across the stem cell workflow.
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Written by Rebecca Quelch and Stefan Przyborski, this poster summarizes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and potential uses.
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