Cardiomyocyte Stem Cells

Induced pluripotent stem cells (iPS cells or iPSCs) can be reprogrammed into human cardiomyocyte-like cells, with the aim of being used to repair damaged tissue caused by myocardial infarction to support heart regeneration. In vivo studies have generated promising results showing proof of principle for regenerative stem cell therapy.

Products
Literature
Cat No Product Name / Activity
3842 5-Azacytidine
DNA methyltransferase inhibitor; induces differentiation of MSCs into cardiomyocytes
3851 Cardiogenol C hydrochloride
Induces cardiomyocyte differentiation in ESCs
4475 Cardionogen 1
Inhibitor of Wnt/β -catenin signaling; induces ES cell cardiac differentiation
3093 Dorsomorphin dihydrochloride
BMP type I receptor inhibitor; promotes cardiomyocyte differentiation in mouse ESCs
1041 1-EBIO
KCa activator; promotes ESC differentiation into cardiomyocytes
4439 ISX 9
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
5068 ITD 1
Selective inhibitor of TGF-beta signaling; induces cardiomyocyte differentiation in ESCs
5214 IWP 4
Potent inhibitor of Wnt/β-catenin signaling; induces cardiomyocyte differentiation of human ESCs and iPSCs
4731 KY 02111
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
4923 Shz 1
Activator of early cardiac genes in pluripotent stem cells; induces differentiation in M-PBMCs
5148 Wnt-C59
Wnt signaling inhibitor; induces differentiation of iPSCs to cardiomyocytes
2293 Zebularine
DNA methyltransferase inhibitor; induces cardiomyocyte differentiation in MSCs

Literature for Cardiomyocyte Stem Cells

Tocris offers the following scientific literature for Cardiomyocyte Stem Cells to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cells

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.