Cardiomyocyte Stem Cells

Induced pluripotent stem cells (iPS cells or iPSCs) can be reprogrammed into human cardiomyocyte-like cells, with the aim of being used to repair damaged tissue caused by myocardial infarction to support heart regeneration. In vivo studies have generated promising results showing proof of principle for regenerative stem cell therapy.

Literature (5)
Cat. No. Product Name / Activity
3084 Anacardic acid
Promotes cardiomyocyte differentiation from mESCs; also histone acetyltransferase (HAT) inhibitor
3842 5-Azacytidine
DNA methyltransferase inhibitor; induces differentiation of MSCs into cardiomyocytes
3093 Dorsomorphin dihydrochloride
Promotes cardiomyocyte differentiation in mouse ESCs; BMP type I receptor inhibitor
1041 1-EBIO
KCa activator; promotes ESC differentiation into cardiomyocytes
4439 ISX 9
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
5068 ITD 1
Selective inhibitor of TGF-beta signaling; induces cardiomyocyte differentiation in ESCs
3533 IWP 2
Promotes promotes cardiomyocyte differentiation from hPSCs; PORCN inhibitor
5214 IWP 4
Potent inhibitor of Wnt/β-catenin signaling; induces cardiomyocyte differentiation of human ESCs and iPSCs
6976 JNJ 10198409
Can be used conversion of fibroblasts to cardiomyocytes in combination with other small molecules
4731 KY 02111
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
7419 Kyoto Probe-1
Fluorescent probe that selectively identifies undifferentiated iPS/ES cells
4287 Poly(I:C)
Accelerates maturation of hPSC-derived cardiomyocytes; synthetic double-stranded RNA (dsRNA)
6577 Pyridone 6
Promotes cardiac differentiation; potent pan-JAK inhibitor
3304 SU 16f
Component of 9C cocktail for conversion of fibroblasts to cardiomyocytes; potent and selective PDGFRβ inhibitor
7690 T 112
Promotes maturation of hiPSC-derived cardiomyocytes; estrogen-related receptor γ agonist
6666 T3
Promotes maturation of hPSC-derived cardiomyocytes; thyroid hormone.
5148 Wnt-C59
Wnt signaling inhibitor; induces differentiation of iPSCs to cardiomyocytes
3748 XAV 939
Promotes cardiomyogenesis; potent tankyrase inhibitor
2293 Zebularine
DNA methyltransferase inhibitor; induces cardiomyocyte differentiation in MSCs

Literature for Cardiomyocyte Stem Cells

Tocris offers the following scientific literature for Cardiomyocyte Stem Cells to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cancer Research Product Guide

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Stem Cell Research Product Guide

Stem Cell Research Product Guide

This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:

  • Self-renewal and Maintenance
  • Differentiation
  • Reprogramming
  • Organoid Generation
  • GMP and Ancillary Material Grade Products
Stem Cells Scientific Review

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cell Workflow Poster

Stem Cell Workflow Poster

Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.

Stem Cells Poster

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.