Autophagy Inhibitors
| Cat. No. | Product Name / Activity |
|---|---|
| 4265 | AS 1842856 |
| Potent and selective Foxo1 inhibitor; suppresses autophagy | |
| 6324 | Autophinib |
| Potent VPS34 inhibitor | |
| 3771 | Azithromycin |
| Autophagy inhibitor; antibiotic | |
| 1334 | Bafilomycin A1 |
| H+-ATPase (vacuolar) inhibitor; also inhibits autophagy | |
| 1544 | (±)-Bay K 8644 |
| L-type Ca2+ channel activator; inhibits autophagy | |
| 4109 | Chloroquine diphosphate |
| Inhibits apoptosis and autophagy | |
| 2656 | Concanamycin A |
| H+-ATPase (vacuolar) inhibitor | |
| 4417 | DBeQ |
| Selective p97 ATPase inhibitor; blocks autophagosome maturation | |
| 4545 | E 64d |
| Cathepsin inhibitor; interferes with autolysosomal digestion | |
| 0786 | Edaravone |
| Autophagy inhibitor; also anti-ischemic and antioxidant | |
| 2473 | GW 4064 |
| Selective farnesoid X receptor (FXR) agonist; suppresses autophagy in nutrient-deprived hepatocytes | |
| 5648 | Hydroxychloroquine sulfate |
| Autophagy inhibitor; also TLR9 inhibitor | |
| 1130 | LY 294002 hydrochloride |
| Prototypical PI 3-kinase inhibitor; inhibits autophagic sequestration | |
| 3982 | Mdivi 1 |
| Autophagy inhibitor; also selective dynamin inhibitor | |
| 3977 | 3-Methyladenine |
| Class III PI 3-kinase inhibitor; also inhibits autophagy | |
| 5153 | ML 240 |
| ATP-competitive inhibitor of p97 ATPase; impairs autophagosome maturation | |
| 5134 | MRT 67307 dihydrochloride |
| Autophagy inhibitor; potent ULK inhibitor; also salt inducible kinase (SIK) inhibitor; | |
| 5067 | MRT 68601 hydrochloride |
| Potent TBK1 inhibitor; also inhibits autophagy | |
| 5780 | MRT 68921 dihydrochloride |
| Autophagy inhibitor; potent ULK inhibitor | |
| 6180 | NMS 873 |
| Potent and selective p97 ATPase (VCP) allosteric inhibitor | |
| 1228 | Nocodazole |
| Microtubule inhibitor; inhibits autophagosome-lysosome fusion | |
| 1190 | Pepstatin A |
| Protease inhibitor; interferes with autolysosomal digestion | |
| 1965 | Simvastatin |
| Autophagy inhibitor; HMG-CoA reductase inhibitor; also AMPK activator | |
| 5197 | Spautin 1 |
| Inhibits autophagy; USP10 and USP13 inhibitor | |
| 1097 | Taxol |
| Promotes assembly and inhibits disassembly of microtubules | |
| 1256 | Vinblastine sulfate |
| Disrupts microtubules; inhibits autophagosome maturation | |
| 1232 | Wortmannin |
| Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1 | |
| 4686 | Xanthohumol |
| p97 ATPase (VCP) inhibitor; impairs autophagosome maturation |
Cancer Research Product Guide
Our Cancer Research Guide highlights over 750 products for cancer research.
Request copyRequest PDFAutophagy Scientific Review
Our Autophagy review summarizes the molecular mechanisms and physiology of autophagy, as well as the role of autophagy in certain disease states.
Request copyRequest PDFAutophagy Life Science Poster
Written by Patricia Boya and Patrice Codogno
Our Autophagy poster summarizes the molecular machinery, physiology and pathology of autophagy, and highlights chemical compounds that modulate autophagy.
Request copyDownload PDFProgrammed Cell Death Life Science Poster
Written by Bram van Raam and Guy Salvesen
Our Programmed Cell Death poster gives a summary of the signaling pathways involved in apoptosis, necroptosis and cell survival.
Request copyDownload PDF