Voltage-gated Sodium (NaV) Channel Blockers

Cat. No. Product Name / Activity
2976 A 803467
Selective NaV1.8 channel blocker
4249 A 887826
Potent voltage-dependent NaV1.8 channel blocker
0890 Amiloride hydrochloride
Na+ channel blocker; also I2 imidazoline ligand
6159 4,9-Anhydrotetrodotoxin
Potent and selective Nav1.6 channel blocker
4804 APETx2
NaV1.8 and NaV1.2 blocker; also blocks ASIC3 channels
4098 Carbamazepine
Inhibitor of neuronal NaV channels; anticonvulsant
1470 Flecainide acetate
Cardiac Na+ channel blocker. Antiarrhythmic
7029 GX 201
Potent and selective Nav1.7 blocker; analgesic
5066 ICA 121431
Potent and selective NaV1.3 and NaV1.1 channel blocker
4913 Jingzhaotoxin III
Selective NaV1.5 channel blocker
3865 Licarbazepine
Active metabolite of oxcarbazepine (Cat. No. 3864)
3057 Lidocaine
Na+ channel blocker
2596 Mexiletine hydrochloride
Na+ channel blocker; antiarrhythmic agent
4691 NAV 26
Selective Nav1.7 channel blocker
5927 NS 383
ASIC blocker; active in vivo
3864 Oxcarbazepine
Anticonvulsant; inhibits Na+ channel activity
4916 PF 04885614
Potent and selective NaV1.8 channel blocker; active in vivo
5931 PF 05089771
Potent and selective Nav1.7 channel blocker
4914 Phrixotoxin 3
Potent blocker of NaV1.2, NaV1.3 and NaV1.5 channels
4023 ProTx II
Selective NaV1.7 channel blocker
1014 QX 314 bromide
Na+ channel blocker
2313 QX 314 chloride
Na+ channel blocker
0768 Riluzole hydrochloride
Na+ channel blocker; also inhibits GABA uptake and glutamate release
4044 Sipatrigine
NaV blocker; neuroprotective
4435 TC-N 1752
NaV channel blocker
1078 Tetrodotoxin
Na+ channel blocker
1069 Tetrodotoxin citrate
Na+ channel blocker; citrate salt of tetrodotoxin (Cat. No. 1078)
2815 Valproic acid, sodium salt
Blocks voltage-gated Na+ channels