Other Proteases

Inhibitors

Cat. No. Product Name / Activity
5630 (Z-LL)2 ketone
Putative inhibitor of signal peptide peptidase
5402 6bK
Insulin degrading enzyme (IDE) inhibitor
5852 Acetyl Pepstatin
High affinity aspartic protease inhibitor
5175 AEBSF
Broad spectrum, irreversible inhibitor of serine proteases
5491 Aliskiren hemifumarate
Potent renin inhibitor; antihypertensive
2511 APC 366
Tryptase inhibitor
4139 Aprotinin
Competitive serine protease inhibitor
1637 Argatroban
Potent thrombin inhibitor
1323 Butabindide oxalate
High affinity CCK-inactivating serine protease inhibitor
3193 Camostat mesylate
Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells
2512 CGS 35066
Endothelin-converting enzyme (ECE) inhibitor
2709 Cilastatin sodium
Dipeptidase inhibitor
0460 Cinanserin hydrochloride
3C-like proteinase inhibitor; also selective 5-HT2 antagonist; antiviral
3501 Decanoyl-RVKR-CMK
Subtilisin/Kex2p-like proprotein convertase inhibitor
4524 EGCG
β-secretase (BACE) inhibitor; inhibits amyloid assembly
1798 Gabexate mesylate
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
6272 KYP 2047
High affinity prolyl oligopeptidase inhibitor; anti-angiogenic, neuroprotective and brain penetrant
1167 Leupeptin hemisulfate
Inhibits trypsin-like/cysteine proteases
7081 LY 2886721 Hydrochloride
Potent and selective β-secretase (BACE) inhibitor
4848 MI 2 (MALT1 inhibitor)
MALT1 inhibitor
3081 Nafamostat mesylate
Serine protease inhibitor; inhibits tryptase
6423 Pep 2-8
Potent PCSK9 inhibitor
1190 Pepstatin A
Aspartic protease inhibitor
3354 PF 429242 dihydrochloride
Competitive inhibitor of SREBP site 1 protease
6333 Phosphoramidon disodium salt
Neutral endopeptidase and endothelin converting enzyme inhibitor
4486 PMSF
Non-selective protease inhibitor; also blocks anandamide metabolism
5772 Sacubitril calcium
Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
2931 Spinorphin
Enkephalin-degrading and ACE inhibitor
6658 Telaprevir
Hepatitis C virus (HCV) protease NS3/4A inhibitor
4954 UAMC 00039 dihydrochloride
Dipeptidyl peptidase II (DPP-II) inhibitor
5563 VTP 27999 trifluoroacetate
Highly potent and selective renin inhibitor
1634 Y-29794 oxalate
Prolyl endopeptidase inhibitor
4645 Z-VRPR-FMK trifluoroacetate salt
Irreversible MALT1 inhibitor

Substrates

Cat. No. Product Name / Activity
3791 Hemopressin (human, mouse)
Bioactive substrate for endopeptidase 24.15, neurolysin and ACE
1764 Hemopressin (rat)
Bioactive substrate for endopeptidase 24.15, neurolysin and ACE
3841 RETF-4NA
Selective chymase substrate