Proteases

Proteases (also known as peptidases or proteinases) are a subgroup of hydrolase enzymes that catalyze the cleavage of peptide bonds within proteins. There are two main subtypes of proteases: exoproteases, which hydrolyze peptide bonds at the terminus of polypeptide chains; and endoproteases, which act internally. Proteases are involved in a vast array of physiological processes, from simple digestion of food to complex signaling cascades such as the apoptotic caspase-activated cascade.

Targets

Literature (1)

Protease Target Files

• γ-Secretase
• 3C and 3CL Proteases
• ACE2
• ADAMs
• Aminopeptidases
• Angiotensin-Converting Enzyme
• Calpains
• Carboxypeptidases
• Caspases
• Cathepsin
• Deubiquitinating Enzymes

• Dipeptidyl Peptidase IV
• Elastases
• Furin
• HIV Protease
• Matrix Metalloproteases
• Papain-like Proteases
• Plasminogen Activator Inhibitor-1
• Proteasome
• TMPRSS2
• Urokinase

Related Targets

• Other Proteases

Literature for Proteases

Tocris offers the following scientific literature for Proteases to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

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Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

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• Angiogenesis
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