Cereblon Targeting Ligands Plus Linkers

Products
Literature
Cat. No. Product Name / Activity
6300 Azido-Thalidomide
Thalidomide-alkylC4-Azide
6637 Pomalidomide - linker 1
Pomalidomide-PEG2-ethylamine
6681 Pomalidomide - linker 2
Pomalidomide-PEG3-carboxylic acid
6682 Pomalidomide - linker 3
Pomalidomide-alkylC5-carboxylic acid
6716 Pomalidomide - linker 4
Pomalidomide-alkylC5-amine
6851 Pomalidomide - linker 7
Pomalidomide-alkylC2-amine
6963 Pomalidomide - linker 8
Pomalidomide-PEG4-ethylamine
6467 Thalidomide - linker 1
Thalidomide-PEG3-ethylamine
6949 Thalidomide - linker 10
Thalidomide-alkylC2-amine
6951 Thalidomide - linker 12
Thalidomide-PEG5-ethylamine
6966 Thalidomide - linker 13
Thalidomide-PEG1-ethylamine
6967 Thalidomide - linker 14
Thalidomide-PEG2-ethylamine
6968 Thalidomide - linker 15
Thalidomide-alkylC6-amine
6468 Thalidomide - linker 2
Thalidomide-PEG4-ethylamine
6469 Thalidomide - linker 3
Thalidomide-alkylC4-amine
6627 Thalidomide - linker 4
Thalidomide-alkylC6-amine
6686 Thalidomide - linker 5
Thalidomide-PEG2-alkyne
6850 Thalidomide - linker 6
Thalidomide-alkylC2-Amine
6917 Thalidomide - linker 9
Thalidomide-alkylC4-amine

Literature for Cereblon Targeting Ligands Plus Linkers

Tocris offers the following scientific literature for Cereblon Targeting Ligands Plus Linkers to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Targeted Protein Degradation

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed.