Cereblon Targeting Ligands Plus Linkers

Products
Literature (2)
Cat. No. Product Name / Activity
6851 Pomalidomide 4'-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7096 Pomalidomide 4'-alkylC3-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7205 Pomalidomide 4'-alkylC3-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7209 Pomalidomide 4'-alkylC4-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6682 Pomalidomide 4'-alkylC5-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6716 Pomalidomide 4'-alkylC5-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7210 Pomalidomide 4'-alkylC6-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7097 Pomalidomide 4'-alkylC7-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7208 Pomalidomide 4'-alkylC7-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7211 Pomalidomide 4'-alkylC8-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6944 Pomalidomide 4'-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7094 Pomalidomide 4'-PEG1-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7203 Pomalidomide 4'-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7212 Pomalidomide 4'-PEG2-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
6637 Pomalidomide 4'-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6681 Pomalidomide 4'-PEG3-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7204 Pomalidomide 4'-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6963 Pomalidomide 4'-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6946 Thalidomide 4'-oxyacetamide-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6850 Thalidomide 4'-ether-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6917 Thalidomide 4'-ether-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6627 Thalidomide 4'-ether-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6686 Thalidomide 4'-ether-PEG2-alkyne
Cereblon ligand with PEG linker and terminal alkyne for onward chemistry
6950 Thalidomide 4'-ether-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6951 Thalidomide 4'-ether-PEG5-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6949 Thalidomide 4'-oxyacetamide-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6469 Thalidomide 4'-oxyacetamide-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6300 Thalidomide 4'-oxyacetamide-alkylC4-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
6968 Thalidomide 4'-oxyacetamide-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6966 Thalidomide 4'-oxyacetamide-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6967 Thalidomide 4'-oxyacetamide-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6467 Thalidomide 4'-oxyacetamide-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6468 Thalidomide 4'-oxyacetamide-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry

Literature for Cereblon Targeting Ligands Plus Linkers

Tocris offers the following scientific literature for Cereblon Targeting Ligands Plus Linkers to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Targeted Protein Degradation

Targeted Protein Degradation Research Product Guide

This brochure highlights the tools and services available from Bio-Techne to support Targeted Protein Degradation research, including:

  • Active Degraders
  • Degrader Building Blocks
  • Custom Degrader Services
  • UPS Proteins and Assays
  • Assays for Protein Degradation
Targeted Protein Degradation

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia