VHL Targeting Ligands Plus Linkers

Products
Literature (1)
Cat. No. Product Name / Activity
6880 VH 032 amide-alkylC10-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6852 VH 032 amide-alkylC2-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6680 VH 032 amide-alkylC4-acid
VHL ligand with alkyl linker and terminal acid for onward chemistry
6465 VH 032 amide-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6985 VH 032 amide-alkylC5-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6853 VH 032 amide-alkylC6-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6890 VH 032 amide-alkylC8-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6879 VH 032 amide-PEG1-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6684 VH 032 amide-PEG2-alkyne
VHL ligand with PEG linker and terminal alkyne for onward chemistry
6907 VH 032 amide-PEG2-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6679 VH 032 amide-PEG3-acid
VHL ligand with PEG linker and terminal acid for onward chemistry
6463 VH 032 amide-PEG3-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6464 VH 032 amide-PEG4-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6909 VH 032 phenol-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6910 VH 032 phenol-alkylC6-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry

Literature for VHL Targeting Ligands Plus Linkers

Tocris offers the following scientific literature for VHL Targeting Ligands Plus Linkers to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Targeted Protein Degradation

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia