Cytokine Other

Cat. No. Product Name / Activity
2446 AS 101
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release
6438 BRD 6989
IL-10 production enhancer; Cdk8 inhibitor
4316 Bropirimine
Immunomodulatory and antitumor compound
4204 BTZO 1
MIF binder
0846 Chicago Sky Blue 6B
MIF inhibitor; also inhibits L-glutamate uptake into synaptic vesicles
6107 CP 424174
Inhibitor of IL-1β post-translational processing; indirectly inhibits NLRP3
4400 (±)-CPSI 1306
Reported macrophage migration inhibitory factor (MIF) inhibitor
5479 CRID3 sodium salt
Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production
2471 ER 27319 maleate
Inhibits TNF-α production
1798 Gabexate mesylate
Inhibits TNF-α production. Also antithrombotic agent
3270 GIT 27
Immunomodulator; reduces production of pro-inflammatory cytokines
5126 iMDK
Suppressor of MDK expression; inhibits PI 3-K signaling
3429 4-IPP
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
5185 JTE 607 dihydrochloride
Cytokine release inhibitor; anti-inflammatory
6305 Lenalidomide
TNF-α inhibitor; inhibits angiogenesis; also cereblon binder
4656 (D)-(+)-Neopterin
Stimulated by IFN-γ; marker of immune activation
1093 Pirfenidone
Antifibrotic agent; regulates cytokine levels in vivo
6302 Pomalidomide
TNF-α inhibitor; also cereblon ubiquitination inhibitor and antiangiogenic
4963 SC 144 hydrochloride
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
6829 (R)-Shikonin
Blocks TNF-α and NF-κB signaling; induces necroptosis; anti-inflammatory
2008 SKF 86002 dihydrochloride
Inhibits human monocyte IL-1 and TNF-α production; p38 MAP kinase inhibitor
3543 Suplatast tosylate
Th2 cytokine synthesis inhibitor; antiasthmatic
0652 Thalidomide
TNF-α synthesis inhibitor; also binds cereblon