Cytokine Receptors

Cytokine receptors are a large family of receptors that are grouped into six categories: type I, type II, immunoglobulin superfamily, tumor necrosis factor family, chemokine and TGF-β receptors.

1. Type I cytokine receptors: include the IL-2 receptor, growth hormone receptor and erythropoietin receptor, are linked to JAK tyrosine kinases.
2. Type II cytokine receptors: include interferon receptors are also linked to JAK tyrosine kinases.
3. Immunoglobulin superfamily receptors: also classed as cell adhesion molecules, and family members include the IL-1 and IL-18 receptors.
4. The tumor necrosis factor family: also known as death receptors as they have a role in the extrinsic apoptotic pathway.
5. Chemokine receptors: G-protein-coupled receptors that have a role in innate and adaptive immunity.
6. TGF-β receptors: serine/threonine kinase-coupled receptors with a role in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death.

External sources of pharmacological information for Cytokine Receptors :

• BJP Guide

Literature for Cytokine Receptors

Tocris offers the following scientific literature for Cytokine Receptors to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

• Cancer Metabolism
• Epigenetics in Cancer
• Receptor Signaling
• Cell Cycle and DNA Damage Repair
• Angiogenesis
• Invasion and Metastasis

• Request copy
• Request PDF
• View all Product Guides & Listings

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

• Chemokine and Cytokine Signaling
• Chemotaxis
• Complement System
• Immune Cell Signaling
• Inflammation

• Request copy
• Request PDF
• View all Product Guides & Listings

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.

• Request copy
• Download PDF
• View all Life Science Posters

Cytokine Receptor Gene Data