Bropirimine

Pricing Availability Delivery Time Qty
Cat.No. 4316 - Bropirimine | C10H8BrN3O | CAS No. 56741-95-8
Description: Immunomodulatory and antitumor compound
Chemical Name: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Immunomodulatory and antitumor compound. Induces interferon (IFN)-α/β production; augments natural killer (NK) cell activity. Orally active.

Technical Data

M. Wt 266.09
Formula C10H8BrN3O
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 56741-95-8
PubChem ID 65457
InChI Key CIUUIPMOFZIWIZ-UHFFFAOYSA-N
Smiles O=C1N=C(N)NC(C2=CC=CC=C2)=C1Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.61 100

Preparing Stock Solutions

The following data is based on the product molecular weight 266.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.76 mL 18.79 mL 37.58 mL
5 mM 0.75 mL 3.76 mL 7.52 mL
10 mM 0.38 mL 1.88 mL 3.76 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Fujioka et al (1995) Antitumor effects of oral administration of an interferon-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma. Cancer Chemother.Pharmacol. 36 7 PMID: 7536641

Tei et al (2002) In vitro antitumor activity of bropirimine against urinary bladder tumor cells. Anticancer Res. 22 1667 PMID: 12168852


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Keywords: Bropirimine, supplier, immunomodulators, immunomodulatory, antitumor, induces, interferons, ifn-a, ifn-alpha, ifn-α, ifn-b, ifn-beta, ifn-β, inducers, IFN, Cytokines, Tocris Bioscience

Citations for Bropirimine

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Pathways for Bropirimine

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