Cat. No. | Product Name / Activity |
---|---|
5397 | A01 |
High affinity Smurf1 inhibitor; enhances BMP signaling | |
5747 | Apcin |
Cdc20 inhibitor; inhibits Cdc20-substrate interaction | |
7715 | C25-140 New |
TRAF6-Ubc13 interaction inhibitor | |
7089 | CSN5i-3 |
Potent and selective CSN5 (COP9 signalosome) inhibitor | |
5636 | GS 143 |
β-TrCP1 ligase inhibitor | |
5433 | Heclin |
HECT E3 ubiquitin ligase inhibitor | |
3503 | HLI 373 |
Hdm2 inhibitor; activates p53-dependent transcription | |
6904 | Idasanutlin |
Potent MDM2 inhibitor; inhibits MDM2-p53 interaction | |
7289 | Nimbolide |
RNF114 inhibitor | |
3984 | Nutlin-3 |
MDM2 antagonist; inhibits MDM2-p53 interaction | |
6075 | Nutlin 3a |
MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984) | |
5047 | PRT 4165 |
Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination | |
5191 | PTC 209 |
Bmi-1 inhibitor; antitumor | |
2443 | RITA |
MDM2-p53 interaction inhibitor | |
7542 | SJ 1008066 |
MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction | |
4375 | SMER 3 |
Selective inhibitor of E3 ubiquitin ligase | |
7192 | SMIP 004 |
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase | |
5332 | SP 141 |
High affinity MDM2 inhibitor | |
7498 | SPOP-i-6lc |
SPOP E3 ubiquitin ligase inhibitor | |
5076 | SZL P1-41 |
Selective Skp2 inhibitor; suppresses E3 ligase activity | |
0652 | Thalidomide |
Binds cereblon; also TNF-α synthesis inhibitor | |
6156 | VH 298 |
High-affinity inhibitor of VHL | |
7055 | WS 383 |
Potent, selective and reversible DCN1-UBC12 interaction inhibitor | |
6719 | YH 239-EE |
MDM2 inhibitor; disrupts MDM2-p53 interaction |