5-HT Transporter Inhibitors
| Cat. No. | Product Name / Activity |
|---|---|
| 2341 | A 80426 mesylate |
| 5-HT uptake inhibitor and α2 antagonist | |
| 4456 | Amitriptyline hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist | |
| 4357 | Bicifadine hydrochloride |
| Noradrenalin, 5-HT and dopamine re-uptake inhibitor | |
| 2322 | BTS 54-505 hydrochloride |
| Potent 5-HT and NA reuptake inhibitor (SNRI); active metabolite of sibutramine (Cat. No. 2290) | |
| 1427 | Citalopram hydrobromide |
| Highly potent and selective 5-HT uptake inhibitor | |
| 0457 | Clomipramine hydrochloride |
| 5-HT reuptake inhibitor | |
| 2833 | Cocaine hydrochloride |
| Inhibitor of monoamine transporters | |
| 4358 | Dapoxetine hydrochloride |
| Selective serotonin reuptake inhibitor (SSRI) | |
| 2695 | Dexfenfluramine hydrochloride |
| 5-HT reuptake inhibitor; also stimulates 5-HT release | |
| 4798 | (S)-Duloxetine hydrochloride |
| Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake | |
| 4796 | Escitalopram oxalate |
| Selective serotonin reuptake inhibitor (SSRI) | |
| 0927 | Fluoxetine hydrochloride |
| 5-HT reuptake inhibitor | |
| 1033 | Fluvoxamine maleate |
| 5-HT reuptake inhibitor | |
| 1588 | Indatraline hydrochloride |
| Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake | |
| 2545 | Lofepramine |
| 5-HT and NA reuptake inhibitor (SNRI) | |
| 3350 | LY 393558 |
| 5-HT reuptake inhibitor; also 5-HT1B and 5-HT1D antagonist | |
| 2148 | (±)-McN 5652 |
| Potent, orally active 5-HT uptake inhibitor; also inhibits noradrenalin and dopamine uptake in vitro | |
| 3027 | (±)-MDMA hydrochloride |
| Inhibitor of 5-HT and dopamine uptake; hallucinogenic | |
| 3286 | Milnacipran hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI) | |
| 2777 | Nefazodone hydrochloride |
| 5-HT uptake inhibitor; also 5-HT2A antagonist; antidepressant | |
| 2141 | Paroxetine maleate |
| Highly potent and selective 5-HT uptake inhibitor | |
| 2395 | Sertraline hydrochloride |
| 5-HT reuptake inhibitor | |
| 2290 | Sibutramine hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI) | |
| 2175 | Tetrabenazine |
| Potent inhibitor of vesicular monoamine transport; depletes 5-HT stores | |
| 2917 | Venlafaxine hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI) | |
| 6202 | Vilazodone hydrochloride |
| Potent SSRI and 5-HT1A partial agonist; antidepressant | |
| 4194 | WY 45233 succinate |
| 5-HT and NA reuptake inhibitor (SNRI) | |
| 1767 | Zimelidine dihydrochloride |
| Selective 5-HT uptake inhibitor |
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Our 5-HT review summarizes the serotonin receptor subtypes and highlights their importance in mediating various physiological & pharmacological processes.
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