5-HT Receptors Scientific Review

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5-HT Receptors Scientific Review

Neuronal 5-HT Receptors and SERT

Nicholas M. Barnes and John F. Neumaier

Review excerpt: "5-hydroxytryptamine...is an ancient biochemical manipulated through evolution to be utilized extensively throughout the animal and plant kingdoms. Mammals employ 5-HT as a neurotransmitter within the central and peripheral nervous systems, and also as a local hormone in numerous other tissues, including the gastrointestinal tract, the cardiovascular system and immune cells."