Monoamine Oxidases

Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of MAO have been identified: MAO-A and MAO-B.

Products
Background
Literature
Gene Data

Inhibitors

Cat No Product Name / Activity
3306 8-(3-Chlorostyryl)caffeine
MAO-B inhibitor. Also A2A inhibitor
0767 Bifemelane hydrochloride
MAO-A and MAO-B inhibitor
1095 (R)-(-)-Deprenyl hydrochloride
MAO-B inhibitor
1132 Harmane
MAO-A and MAO-B inhibitor
2460 Lazabemide hydrochloride
Selective MAO-B inhibitor
4395 Moclobemide
Reversible MAO-A inhibitor
0724 Pirlindole mesylate
MAO-A inhibitor
4308 Rasagiline mesylate
Selective, irreversible MAO-B inhibitor
0723 Tetrindole mesylate
MAO-A inhibitor
3852 Tranylcypromine hydrochloride
Irreversible inhibitor of MAO-A, MAO-B and LSD1

Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of monoamine oxidase have been identified: MAO-A and MAO-B. Both are found in neurons and astroglia, with MAO-A also found in the liver, gastrointestinal tract and placenta and MAO-B in blood platelets. Abnormal regulation of MAOs in the body has been associated with depression, substance abuse, attention deficit disorder, and irregular sexual maturation.

Literature for Monoamine Oxidases

Neurodegeneration

Neurodegeneration Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

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Monoamine Oxidase Gene Data

Gene Species Gene Symbol Gene Accession No. Protein Accession No.
MAO-A Human MAOA NM_000240 P21397
Mouse Maoa NM_173740 Q64133
Rat Maoa XM_343764 P21396
MAO-B Human MAOB NM_000898 P27338
Mouse Maob NM_172778 Q8BW75
Rat Maob NM_013198 P19643