Monoamine Oxidases

Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of MAO have been identified: MAO-A and MAO-B.

Products
Background
Literature
Gene Data

Inhibitors

Cat. No. Product Name / Activity
0767 Bifemelane hydrochloride
Non-selective MAO inhibitor
3306 8-(3-Chlorostyryl)caffeine
MAO-B inhibitor; also A2A inhibitor
1095 (R)-(-)-Deprenyl hydrochloride
MAO-B inhibitor
1132 Harmane
Non-selective MAO inhibitor
2460 Lazabemide hydrochloride
Selective MAO-B inhibitor
6067 M 30 dihydrochloride
Potent and non-selective MAO inhibitor; also an iron chelator and antioxidant
4395 Moclobemide
Reversible MAO-A inhibitor
0724 Pirlindole mesylate
MAO-A inhibitor
4308 Rasagiline mesylate
Selective and irreversible MAO-B inhibitor
0723 Tetrindole mesylate
MAO-A inhibitor
3852 Tranylcypromine hydrochloride
Irreversible and non-selective MAO inhibitor; also inhibits LSD1

Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of monoamine oxidase have been identified: MAO-A and MAO-B. Both are found in neurons and astroglia, with MAO-A also found in the liver, gastrointestinal tract and placenta and MAO-B in blood platelets. Abnormal regulation of MAOs in the body has been associated with depression, substance abuse, attention deficit disorder, and irregular sexual maturation.

External sources of pharmacological information for Monoamine Oxidases :

    Literature for Monoamine Oxidases

    Tocris offers the following scientific literature for Monoamine Oxidases to showcase our products. We invite you to request* or download your copy today!

    *Please note that Tocris will only send literature to established scientific business / institute addresses.


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    Monoamine Oxidase Gene Data

    Gene Species Gene Symbol Gene Accession No. Protein Accession No.
    MAO-A Human MAOA NM_000240 P21397
    Mouse Maoa NM_173740 Q64133
    Rat Maoa XM_343764 P21396
    MAO-B Human MAOB NM_000898 P27338
    Mouse Maob NM_172778 Q8BW75
    Rat Maob NM_013198 P19643