You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Indatraline hydrochloride
Indatraline hydrochloride is a potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (Ki values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo.
Compound Libraries for Indatraline hydrochloride
Technical Data for Indatraline hydrochloride
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Indatraline hydrochloride
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|water||3.29||10 with gentle warming|
Preparing Stock Solutions for Indatraline hydrochloride
The following data is based on the product molecular weight 328.67. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.04 mL||15.21 mL||30.43 mL|
|5 mM||0.61 mL||3.04 mL||6.09 mL|
|10 mM||0.3 mL||1.52 mL||3.04 mL|
|50 mM||0.06 mL||0.3 mL||0.61 mL|
Product Datasheets for Indatraline hydrochloride
References for Indatraline hydrochloride
References are publications that support the biological activity of the product.
Gu et al (2000) Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. J.Med.Chem. 43 4868 PMID: 11123996
Hyttel and Larsen (1985) Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of DA, noradrenaline and serotonin. J.Neurochem. 44 1615 PMID: 2580950
Negus et al (1999) Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys. J.Pharmacol.Exp.Ther. 291 60 PMID: 10490887
If you know of a relevant reference for Indatraline hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Indatraline hydrochloride, Indatraline hydrochloride supplier, Potent, noradrenalin, noradrenaline, reuptake, inhibitors, inhibits, 5-HT, dopamine, Noradrenalin, Transporters, NET, Adrenergic, Monoamine, Neurotransmitter, DAT, Dopamine, Serotonin, SERT, 5-Hydroxytryptamine, Lu19-005, Lu, 19-005, 1588, Tocris Bioscience
Citations for Indatraline hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Indatraline hydrochloride. Do you know of a great paper that uses Indatraline hydrochloride from Tocris? Please let us know.
Reviews for Indatraline hydrochloride
There are currently no reviews for this product. Be the first to review Indatraline hydrochloride and earn rewards!
Have you used Indatraline hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.