Cancer Stem Cells

More Information »Cancer stem cells (CSCs), also known as tumor initiation cells (TICs), are undifferentiated cancer cells that can self-renew and differentiate into bulk tumor cells. They are thought to have a role in the resistance of tumors to therapy, and for disease recurrence.

Cancer Stem Cell Products

Product Name / Activity
5802 A37
ALDH1A1 inhibitor; disrupts spheroid formation of ovarian cancer cells
5336 BRD 7116
Inhibitor of leukemia stem cell activity
1623 Cyclopamine
Inhibitor of Hedgehog (Hh) signaling; depletes stem-like cancer cells in glioblastoma
1368 Geldanamycin
Selective Hsp90 inhibitor; breast cancer stem cell inhibitor
1803 ITE
Induces stem-like cancer cell differentiation; also inhibits TGF--induced human myofibroblast differentiation
5727 MC 1742
Induces CSC apoptosis; also stimulates CSC osteogenic differentiation
4829 ML 239
Breast cancer stem cell inhibitor
5522 Napabucasin
Blocks cancer stem cell self-renewal; STAT3 inhibitor
4079 Niclosamide
Inhibits AML stem cells; STAT3 and mTORC1 signaling inhibitor
4189 SC 26196
Selective Δ6 desaturase inhibitor; eliminates cancer stem cells from ovarian cancer cell lines
5207 STF 118804
Depletes leukemia stem cells; NAMPT inhibitor
3070 Thioridazine hydrochloride
Selective inducer of CSC differentiation; anticancer agent
5960 TMI 1
Selectively cytotoxic towards CSCs
5328 TY 52156
Inhibits S1P-induced breast cancer stem cell expansion; S1P3 receptor antagonist
5305 Verteporfin
Suppresses cancer stem cell properties; YAP inhibitor
6111 Zoledronic Acid
Inhibits breast cancer cell renewal via inactivation of NF-κB; also potent FPP synthase inhibitor
Related Categories

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Stem Cell Toolbox

80 Stem Cell modulators supplied pre-dissolved in DMSO

Tocriscreen Stem Cell  Toolbox

Includes many of the latest compounds available for stem cell research. Covers compounds for stem cell differentiation, signaling and reprogramming.

divider line

Stem Cells Review

Written by K. Clarke et al

Stem Cells Scientific Review

Our Stem Cells review gives an overview of the use of small molecules in the control of stem cell growth & differentiation and somatic cell reprogramming. Request copy or view PDF today.

divider line

Bio-Techne Events

ISSCR 2017

ISSCR 2017

June 14 - 17, 2017

Boston, MA, USA

Booth: 419