Inflammasomes Inhibitors

Cat. No. Product Name / Activity
6774 16673-34-0 NLRP3i
NLRP3 inflammasome inhibitor
6827 Artesunate
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
1744 Bay 11-7821
Inhibits NLRP3 inflammasome activation; binds and inhibits gasdermin D
1364 Colchicine
Suppresses NLRP3 inflammasome; anti-inflammatory; also promotes microtubule depolymerization
5479 CRID3 sodium salt
Potent NLRP3 inflammasome inhibitor
6436 CY 09
NLRP3 inhibitor; active in vivo
6902 Dapansutrile
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
3807 Disulfiram
Pyroptosis inhibitor; binds gasdermin D and inhibits pore formation
6341 INF 39
Irreversible NLRP3 inhibitor
6172 INF 4E
Caspase-1 and NLRP3 inflammasome inhibitor
2877 MNS
Inhibits NLRP3 inflammasome activation; also selective inhibitor of Src and Syk
6722 NBC 19
Potent NLRP3 inflammasome inhibitor
6925 NBC 6
NLRP3 inflammasome inhibitor
5025 Necrosulfonamide
Pyroptosis inhibitor; binds gasdermin D and inhibits pore formation
6924 Oridonin
High affinity NLRP3 inflammasome inhibitor
6012 OXSI 2
Inhibits assembly of NLRP3 inflammasomes; also potent Syk kinase inhibitor
6829 (R)-Shikonin
NLRP3 inhibitor; suppresses inflammasome activation
2163 Z-VAD-FMK
Irreversible caspase inhibitor; cell-permeable