Purinergic (P2X) Receptor Antagonists

Cat. No. Product Name / Activity
6493 A 317491 sodium salt
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
2972 A 438079 hydrochloride
Competitive P2X7 antagonist
3701 A 740003
Potent and selective P2X7 antagonist
4473 A 804598
Potent and selective P2X7 antagonist
3323 AZ 10606120 dihydrochloride
Potent P2X7 antagonist
3317 AZ 11645373
Potent and selective human P2X7 antagonist
7573 BAY 1797
Selective P2X4 antagonist
3579 5-BDBD
Potent and selective P2X4 antagonist
5545 BX 430
Selective P2X4 allosteric antagonist
0845 Evans Blue tetrasodium salt
P2X antagonist; also non-NMDA iGluR antagonist; inhibits L-glutamate uptake into synaptic vesicles
2611 IMD 0354
P2X1, P2X4 and P2X7 antagonist; also inhibitor of IKKβ
5299 JNJ 47965567
Potent and selective P2X7 antagonist; brain penetrant
1277 KN-62
Non-competitive P2X7 antagonist
1240 NF 023
Selective and competitive P2X1 antagonist
2548 NF 110
Potent P2X3 antagonist
2450 NF 157
Selective P2Y11 and P2X1 antagonist
1199 NF 279
Potent and selective P2X1 antagonist
1391 NF 449
Highly selective P2X1 antagonist
0625 PPADS tetrasodium salt
Non-selective P2 antagonist
0683 iso-PPADS tetrasodium salt
Non-selective P2X antagonist
1309 PPNDS
Potent and selective P2X1 antagonist
4391 Ro 51
Potent P2X3 and P2X2/3 antagonist
3052 RO-3
Selective P2X3 and P2X2/3 antagonist
2464 TNP-ATP triethylammonium salt
Potent and selective P2X antagonist