Estrogen Signaling Pathway

Pathway Key Download PDF

Estrogen is a steroid hormone that is responsible for the regulation of growth, differentiation and function of the reproductive system and several other target tissues. Estrogen receptors have both transcriptional and non-genomic functions and response to both estrogen and other signals that arise from growth factor signaling pathways. Estrogen signaling is often dysregulated in breast cancer and osteoporosis.

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Signaling Pathway Key
Stimulates
Stimulates
Multistep Upregulation
Multistep Upregulation
Multistep Activation
Multistep Activation
Translocates
Translocates
Other Enzyme
Other Enzyme
Kinase
Kinase
Transcription Factor
Transcription Factor
Enzyme-linked Receptor
Enzyme-linked Receptor
Other Protein
Other Protein
Nuclear Receptor
Nuclear Receptor