TRPV Channel Antagonists

Cat. No. Product Name / Activity
5781 A 425619
Potent TRPV1 antagonist
4319 A 784168
Potent and selective TRPV1 antagonist
4330 AMG 21629
Potent and selective TRPV1 antagonist
5995 AMG 517
Potent TRPV1 antagonist
2316 AMG 9810
Potent and selective TRPV1 competitive antagonist
3875 BCTC
TRPV1 antagonist
0464 Capsazepine
TRPV antagonist; also activator of ENaCδ
7199 (±)-Eriodictyol
Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling
5106 GSK 2193874
Potent and selective TRPV4 antagonist; orally active
4100 HC 067047
Potent and selective TRPV4 antagonist
3361 JNJ 17203212
Reversible, competitive and potent TRPV1 antagonist
1577 L-R4W2
TRPV1 antagonist peptide
3746 RN 1734
Selective TRPV4 antagonist
5678 RN 9893 hydrochloride
Potent and selective TRPV4 antagonist
1439 Ruthenium Red
Blocks capsaicin-activated cation channels
1615 SB 366791
Potent and selective TRPV1 competitive antagonist
3265 SB 452533
Potent TRPV1 antagonist
6990 SET 2
Selective TRPV2 antagonist
4729 α-Spinasterol
TRPV1 antagonist; active in vivo
1098 Tranilast
Antiallergic; inhibits TRPV2-mediated responses
6831 TRPV3 74a
Selective TRPV3 antagonist; brain penetrant