Glycogen Synthase Kinase 3 Inhibitors

Cat. No. Product Name / Activity
4083 3F8
Potent and selective GSK-3β inhibitor
4431 A 1070722
Highly potent, selective GSK-3 inhibitor
6400 Alsterpaullone
GSK-3β inhibitor; also inhibits CDK1/2 and Lck
3966 AR-A 014418
Selective GSK-3 inhibitor
7650 AZD 2858
Highly potent GSK-3 inhibitor; inhibits tau phosphorylation
3194 BIO
Potent GSK-3 inhibitor; also inhibits cdks
3874 BIO-acetoxime
Selective GSK-3α/β inhibitor
6695 CHIR 98014
Highly potent and selective GSK-3 inhibitor
4423 CHIR 99021
Highly selective GSK-3 inhibitor; acts as Wnt activator
4953 CHIR 99021 trihydrochloride
Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
1813 Indirubin-3'-oxime
GSK-3β inhibitor; also inhibits cdks and other protein kinases
1398 Kenpaullone
GSK-3β inhibitor; also inhibits cdks
4740 Lithium carbonate
Mood stabilizer; inhibits GSK-3 in vivo
3873 MeBIO
Inactive analog of BIO (Cat. No. 3194)
1616 SB 216763
Potent, selective GSK-3 inhibitor
1617 SB 415286
Potent, selective GSK-3 inhibitor
4353 TC-G 24
Potent and selective GSK-3β inhibitor
3869 TCS 2002
Potent GSK-3β inhibitor
4221 TCS 21311
GSK-3β inhibitor. Also inhibits PKC and JAK3
6092 TDZD 8
Selective non-ATP competitive inhibitor of GSK 3β
7405 TWS 119
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation