Checkpoint Control Kinase Inhibitors

Cat. No. Product Name / Activity
7589 Adavosertib
Potent and selective Wee1 inhibitor
5198 AZ 20
Potent and selective ATR kinase inhibitor; antitumor
3994 AZ 3146
Potent and selective Mps1 inhibitor
6330 AZ 5704
Potent and selective ATM kinase inhibitor; orally bioavailable.
7549 BAY 1816032
Potent and selective BUB1 kinase inhibitor
3544 KU 55933
Potent and selective ATM kinase inhibitor
6454 LY 2603618
Potent and selective Chk1 inhibitor
3190 Mirin
MRN-ATM pathway inhibitor
3712 NU 7441
Potent and selective DNA-PK inhibitor
3785 PD 166285 dihydrochloride
Wee1 inhibitor; also inhibits Src, FGFR and PDGFRβ
2694 PD 407824
Potent and selective inhibitor of Chk1 and Wee1
2930 PI 103 hydrochloride
Inhibitor of DNA-PK, mTOR and PI 3-kinase
2560 SB 218078
Chk1 inhibitor