Checkpoint Control Kinase Inhibitors

Cat. No. Product Name / Activity
5198 AZ 20
Potent and selective ATR kinase inhibitor; antitumor
3994 AZ 3146
Potent and selective Mps1 inhibitor
6330 AZ 5704
Potent and selective ATM kinase inhibitor; orally bioavailable.
5199 AZD 7762 hydrochloride
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2
4968 CCT 241533 dihydrochloride
Potent Chk2 inhibitor
3271 Compound 401
Selective DNA-PK and mTOR inhibitor
2088 DMNB
DNA-PK inhibitor
4840 KU 0060648
Dual DNA-PK and PI 3-K inhibitor
3544 KU 55933
Potent and selective ATM kinase inhibitor
4176 KU 60019
Potent ATM kinase inhibitor
6454 LY 2603618
Potent and selective Chk1 inhibitor
3190 Mirin
MRN-ATM pathway inhibitor
5562 Mps BAY 2a
Potent and selective Mps1 kinase inhibitor
5142 Mps1-IN-1 dihydrochloride
Selective Mps1 kinase inhibitor
3034 NSC 109555 ditosylate
Selective Chk2 inhibitor
2828 NU 7026
Selective DNA-PK inhibitor
3712 NU 7441
Potent and selective DNA-PK inhibitor
3785 PD 166285 dihydrochloride
Wee1 inhibitor; also inhibits Src, FGFR and PDGFRβ
2694 PD 407824
Potent and selective inhibitor of Chk1 and Wee1
4277 PF 477736
Selective Chk1 inhibitor
2930 PI 103 hydrochloride
Inhibitor of DNA-PK, mTOR and PI 3-kinase
2560 SB 218078
Chk1 inhibitor
4750 TC Mps1 12
Potent and selective Mps1 kinase inhibitor; orally active
3038 TCS 2312
Potent Chk1 inhibitor