New ProductsView all New Products Alphabetically
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 5860 | 7rh | Dec 2019 |
| Potent and selective DDR1 inhibitor; orally bioavailable | ||
| 6473 | A 410099.1 amide-PEG2-amine | Nov 2019 |
| A 410099.1 amide-PEG2-amine | ||
| 6472 | A 410099.1 amide-PEG3-amine | Nov 2019 |
| A 410099.1 amide-PEG3-amine | ||
| 6474 | A 410099.1 amide-alkylC4-amine | Nov 2019 |
| A 410099.1 amide-alkylC4-amine | ||
| 6471 | A 410099.1, amine | Nov 2019 |
| Functionalized IAP ligand for PROTACs | ||
| 6931 | AF 64394 | Dec 2019 |
| Potent and selective GPR3 inverse agonist | ||
| 6481 | AP 14145 hydrochloride | Nov 2019 |
| KCa2 channel negative allosteric modulator | ||
| 4265 | AS 1842856 | Nov 2019 |
| Potent and selective Foxo1 inhibitor; orally bioavailable | ||
| 6870 | AZ 12799734 | Nov 2019 |
| Potent TGF-βRI inhibitor | ||
| 6826 | AZ 1729 | Mar 2020 |
| FFA2 allosteric agonist; displays bias for the Gi signaling pathway | ||
| 7121 | 7-Aminoactinomycin D | Feb 2020 |
| Fluorescent DNA stain | ||
| 7031 | Amyloid β-Peptide (1-37) (human) | Nov 2019 |
| Amyloid β-protein fragment | ||
| 6791 | BC-LI-0186 | Feb 2020 |
| Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor | ||
| 6974 | BMS 986094 | Oct 2019 |
| Prodrug of HCV RNA polymerase inhibitor 2'-C-methyl guanosine triphosphate; potent HCV replication inhibitor | ||
| 6940 | BTD | Oct 2019 |
| Selective TRPC5 activator | ||
| 7040 | C 176 | Feb 2020 |
| mSTING antagonist | ||
| 6725 | CHDI 00390576 | Dec 2019 |
| Potent and selective class IIa HDAC inhibitor; brain penetrant | ||
| 6758 | CLP 290 | Mar 2020 |
| K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242) | ||
| 7163 | Chroman 1 | Mar 2020 |
| Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis | ||
| 6457 | Cyanine 3 Tyramide | Jan 2020 |
| Orange fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6458 | Cyanine 5 Tyramide | Jan 2020 |
| Red fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6982 | Cyclosporin H | Oct 2019 |
| Enhances lentiviral transduction | ||
| 7090 | Digoxigenin-11-dUTP | Mar 2020 |
| Hapten modified dUTP for ISH | ||
| 6456 | Fluorescein Tyramide | Jan 2020 |
| Green fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6574 | Fluorescein-NAD+ | Oct 2019 |
| Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays | ||
| 6961 | FzM1.8 | Dec 2019 |
| Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness | ||
| 7071 | GSK 2239633A | Dec 2019 |
| Potent CCR4 antagonist | ||
| 6110 | HJC 0416 hydrochloride | Feb 2020 |
| STAT3 inhibitor | ||
| 7015 | IA-Alkyne | Jan 2020 |
| Broad spectrum cysteine reactive probe | ||
| 6976 | JNJ 10198409 | Mar 2020 |
| Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases | ||
| 7088 | Janelia Fluor® 646, Azide | Feb 2020 |
| Red dye (Reactive group: azide). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, and live cell imaging | ||
| 6993 | Janelia Fluor® 646, free acid | Feb 2020 |
| Red dye (Reactive group: free acid). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging | ||
| 7002 | KYA 1797K | Dec 2019 |
| Wnt/β-catenin signaling inhibitor | ||
| 7065 | Kainic acid (synthetic) | Oct 2019 |
| Kainate agonist; excitant and neurotoxin | ||
| 6691 | LP 922056 | Oct 2019 |
| Notum inhibitor; activates Wnt signaling | ||
| 6964 | LY 2119620 | Jan 2020 |
| Positive allosteric modulator of M2 and M4 receptors | ||
| 7045 | (±)-α-Lipoamide | Oct 2019 |
| Phase-separated condensate modifier; orally bioavailable | ||
| 7044 | (±)-α-Lipoic acid | Nov 2019 |
| Liquid-liquid phase separated condensate modifier; reduces stress granule formation | ||
| 6799 | MB 0223 | Dec 2019 |
| Dynamin-related GTPase DRP1 partial inhibitor | ||
| 7053 | MM 07 | Dec 2019 |
| Apelin receptor biased agonist; exhibits bias for the G protein pathway | ||
| 6858 | MMG 11 | Jan 2020 |
| TLR2 antagonist | ||
| 7070 | Mirabegron | Nov 2019 |
| Potent and selective β3 agonist | ||
| 6863 | N6-Cyclohexyladenosine | Nov 2019 |
| High affinity A1 receptor agonist | ||
| 6925 | NBC 6 | Jan 2020 |
| NLRP3 inflammasome inhibitor | ||
| 5746 | NESS 0327 | Feb 2020 |
| Ultra-high affinity and selective CB1 antagonist | ||
| 6900 | NNMTi | Dec 2019 |
| Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation | ||
| 7049 | Nintedanib | Dec 2019 |
| Potent VEGFR, PDGFR and FGFR inhibitor | ||
| 7013 | OptoBI-1 | Nov 2019 |
| Photoswitchable TRPC3/6/7 agonist | ||
| 6897 | P110 | Oct 2019 |
| Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable | ||
| 7007 | PDD 00017238 | Dec 2019 |
| High affinity and potent PARG inhibitor | ||
| 7009 | PDD 00031705 | Dec 2019 |
| Negative control for PDD 00017238 (Cat. No. 7007). | ||
| 6220 | PM 226 | Jan 2020 |
| Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective | ||
| 6372 | PSB CB5 | Mar 2020 |
| Selective GPR18 antagonist | ||
| 7038 | Palonosetron hydrochloride | Feb 2020 |
| Highly potent and high affinity 5-HT3 antagonist | ||
| 6991 | Poly Vinyl Alcohol | Dec 2019 |
| Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion | ||
| 7066 | RCGD 423 | Nov 2019 |
| gp130 modulator; activates JAK/STAT signaling | ||
| 6833 | RO 5263397 hydrochloride | Feb 2020 |
| Potent TA1 receptor agonist | ||
| 7050 | Ribociclib | Dec 2019 |
| Dual cdk4/cdk6 inhibitor; orally bioavailable | ||
| 7064 | Ruxolitinib | Feb 2020 |
| Potent and selective JAK1/JAK2 inhibitor; orally bioavailable | ||
| 7048 | Ruxolitinib phosphate | Feb 2020 |
| Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor | ||
| 6860 | SB 290157 trifluoroacetate | Dec 2019 |
| Potent C3a receptor antagonist | ||
| 7039 | SK 609 | Feb 2020 |
| Dopamine D3 receptor biased agonist | ||
| 6398 | SKA 121 | Jan 2020 |
| Positive allosteric modulator of KCa3.1 channels | ||
| 6775 | ST 045849 | Dec 2019 |
| O-GlcNAc transferase (OGT) inhibitor | ||
| 7119 | Sorbic acid | Nov 2019 |
| Activator of hFFA2-DREADDs | ||
| 6729 | TAN 452 | Dec 2019 |
| Potent and selective peripherally acting δ opioid antagonist; antianalgesic. | ||
| 6847 | TAT-GluA2 3Y | Oct 2019 |
| Inhibitor of AMPA receptor endocytosis | ||
| 6981 | TL 0259 | Dec 2019 |
| Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable | ||
| 6670 | TP 238 | Mar 2020 |
| CECR2 and BPTF/FALZ inhibitor | ||
| 6875 | TRPC6-PAM-C20 | Dec 2019 |
| Selective TRPC6 positive allosteric modulator | ||
| 6586 | Targapremir 210 | Dec 2019 |
| Inhibits formation of miR-210 | ||
| 7051 | Tasquinimod | Jan 2020 |
| High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic | ||
| 6946 | Thalidomide 4'-oxyacetamide-alkylC8-amine | Nov 2019 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7150 | Tocriscreen 2.0 Max | Jan 2020 |
| A library of 1280 biologically active compounds (250 μL 10 mM DMSO solutions) | ||
| 7152 | Tocriscreen 2.0 Micro | Jan 2020 |
| A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions) | ||
| 7151 | Tocriscreen 2.0 Mini | Jan 2020 |
| A library of 1280 biologically active compounds (50 μL 10 mM DMSO solutions) | ||
| 6985 | VH 032 amide-alkylC5-amine | Jan 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7074 | VH 032 amide-alkylC7-amine | Mar 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 6911 | VH 032, phenol | Mar 2020 |
| Hydroxyl functionalized VHL ligand | ||
| 6952 | VH 101, phenol | Jan 2020 |
| Hydroxyl functionalized VHL ligand | ||
| 6895 | VU 0424465 | Oct 2019 |
| Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity | ||
| 6932 | VU 0467485 | Oct 2019 |
| Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant | ||
| 6928 | VU 6001966 | Feb 2020 |
| Potent and selective negative allosteric modulator of mGlu2 receptors | ||
| 6936 | VZ 185 | Oct 2019 |
| Potent and selective BRD7/9 Degrader | ||
| 7026 | Veliparib dihydrochloride | Dec 2019 |
| High affinity PARP-1 and -2 inhibitor; orally bioavailable | ||
| TB3748-GMP | XAV 939 | Jan 2020 |
| XAV 939 synthesized to cGMP guidelines | ||
| 6739 | YNT 185 | Mar 2020 |
| Potent and selective OX2 agonist | ||
| 6971 | aTAG 4531 | Nov 2019 |
| Degrader of MTH1 fusion proteins for use within the aTAG system | ||
| 6939 | cis-VZ 185 | Mar 2020 |
| Negative control for VZ 185 (Cat. No. 6936) | ||
| 6912 | dTAG-7 | Dec 2019 |
| First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation | ||
| 7162 | iFSP1 | Feb 2020 |
| Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer |