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Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7376 | 2A3 | Mar 2022 |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable | ||
| TB2939-RMU | A 83-01 | May 2022 |
| A 83-01 synthesized to Ancillary Material Grade | ||
| 7680 | ABT 263 | May 2022 |
| High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor | ||
| 6923 | AMZ 30 | Jun 2022 |
| Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor | ||
| 7650 | AZD 2858 | May 2022 |
| Highly potent GSK-3 inhibitor; inhibits tau phosphorylation | ||
| 7479 | Ac4ManNAz | Jul 2022 |
| Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe | ||
| 7553 | Ac4ManNDAz | Apr 2022 |
| Photo-crosslinking probe for studying glycoproteins and glycolipids | ||
| 7589 | Adavosertib | Feb 2022 |
| Potent and selective Wee1 inhibitor | ||
| 7678 | 5-Amino-Thalidomide | Jul 2022 |
| Cereblon ligand with amine on C5 for onward chemistry | ||
| 7664 | 3-Azido-7-hydroxycoumarin | Aug 2022 |
| Click-reactive fluorescent dye | ||
| 7483 | BDY FL VH032 | Mar 2022 |
| High-affinity VHL fluorescent probe for TR-FRET and FP assays | ||
| 6878 | BMS 466442 | May 2022 |
| Potent and selective inhibitor of asc-1 | ||
| 7528 | BSJ-4-116 | Jul 2022 |
| Selective CDK12 PROTAC® Degrader | ||
| 7529 | BSJ-4-116-NC | Jul 2022 |
| Negative control for BSJ-4-116 (Cat. No. 7528). | ||
| 7686 | BromoTag® AGB1 | Apr 2022 |
| Potent and selective Degrader of Brd4BD2 L387A fusion proteins (BromoTag®) | ||
| 7687 | BromoTag® cis-AGB1 | Apr 2022 |
| Negative control for BromoTag® AGB1 (Cat.No. 7686) | ||
| 7512 | 3-Bromopyruvate | Apr 2022 |
| MCT1 inhibitor; also inhibits hexokinase II | ||
| 7692 | C26-A6 | Jul 2022 |
| Disrupts MTDH and SND1 interaction, enhances immune surveillance | ||
| 7494 | CIA 1 | Apr 2022 |
| COUP-TFII inhibitor | ||
| 7089 | CSN5i-3 | Apr 2022 |
| Potent and selective CSN5 (COP9 signalosome) inhibitor | ||
| 7532 | CSN5i-3-NEG | Apr 2022 |
| Negative control for CSN5i-3 (Cat. No. 7089) | ||
| 7137 | Cambinol | May 2022 |
| nSMase2 inhibitor | ||
| 6781 | Capzimin dimer | Jul 2022 |
| Selective proteasome inhibitor | ||
| 7506 | Click N-Acetylmuramic acid - azide | Jul 2022 |
| Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes. | ||
| 7485 | Covidcil-19 | Apr 2022 |
| Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency | ||
| 7726 | DMSO, Cell Cryopreserve Grade | Apr 2022 |
| Intracellular cryoprotective agent | ||
| 7236 | Digoxigenin Tyramide | Jul 2022 |
| Reagent used for Tyramide Signal Amplification in IHC, ICC and ISH | ||
| 7714 | EDA-DA | May 2022 |
| Unnatural dipeptide building block with alkyne group for functionalizing peptidoglycan | ||
| 7010 | EM 163 | Mar 2022 |
| TIR-TIR interaction inhibitor | ||
| 6795 | GeA-69 | Jul 2022 |
| Selective allosteric PARP14 inhibitor | ||
| 7685 | IND 1316 | Jul 2022 |
| AMPK activator | ||
| TB4439-RMU | ISX 9 | Mar 2022 |
| ISX 9 synthesized to Ancillary Material Grade | ||
| 7196 | Indinavir sulfate | Jun 2022 |
| Potent and selective HIV-1 and HIV-2 protease inhibitor | ||
| 7510 | Indocyanine green | Jun 2022 |
| Near-infrared fluorescent dye | ||
| 7689 | (+)-JQ1 bump, acid functionalized | May 2022 |
| Functionalized BET bromodomain ligand; precursor for Tag Degraders | ||
| 7682 | JQAD1 | Feb 2022 |
| Potent and selective EP300 Degrader | ||
| TB6053-GMP | LDN 193189 | Apr 2022 |
| LDN 193189 synthesized to cGMP guidelines | ||
| 7652 | Linsitinib | Apr 2022 |
| Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor | ||
| 7492 | Lomitapide mesylate | May 2022 |
| Potent microsomal triglyceride transfer protein (MTP) inhibitor | ||
| 7695 | Mpro 61 | Jul 2022 |
| Potent non-covalent inhibitor of SARS-CoV-2 main protease | ||
| 7488 | MRTX 849 | Feb 2022 |
| Mutation-selective inhibitor of KRASG12C | ||
| 7681 | Mandi | Jul 2022 |
| Highly efficient chemical inducer of proximity (CIP) | ||
| 7641 | Mito-HE | May 2022 |
| Fluorescent mitochondrial superoxide indicator in live cells | ||
| 7586 | Molnupiravir | Mar 2022 |
| Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection | ||
| 7716 | N-methylated pomalidomide | Jul 2022 |
| Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control | ||
| 7538 | NBD-PE | Jul 2022 |
| Single tail (16:0) phospholipid derivative with a fluorophore (NBD) on the head | ||
| 7301 | NHS-LC-Biotin | Jul 2022 |
| Amine reactive biotinylation reagent, cell permeable | ||
| 7668 | Opicapone | Aug 2022 |
| COMT inhibitor | ||
| 7663 | Ozanimod | May 2022 |
| Potent and selective S1P1 and S1P5 agonist | ||
| 7629 | Panobinostat | Jun 2022 |
| Pan-histone deacetylase inhibitor | ||
| 7590 | Pexidartinib | Apr 2022 |
| Potent CSF-1R inhibitor | ||
| 7392 | 5-Ph-IAA | May 2022 |
| Selective and potent TAG Degrader for auxin-inducible degron 2 system | ||
| 7201 | Phalloidin-Janelia Fluor® 646 | Mar 2022 |
| Red fluorescent F-actin probe | ||
| 7670 | Phenyl-glutarimide 4'-oxyacetic acid | Jun 2022 |
| Functionalized cereblon ligand for PROTAC development | ||
| 7362 | Phototrexate | Mar 2022 |
| Photoswitchable inhibitor of human dihydrofolate reductase | ||
| 7667 | Pimavanserin | Mar 2022 |
| Selective 5-HT2A inverse agonist | ||
| 7711 | Polybrene | Jul 2022 |
| Viral transduction enhancer | ||
| 7732 | Pomalidomide 4'-alkylC10-amine | Jul 2022 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7630 | Pridopidine | Mar 2022 |
| Highly selective σ1 agonist | ||
| 7701 | RAGE 229 | Jun 2022 |
| ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice | ||
| 7679 | RECTAS | May 2022 |
| IKBKAP pre-mRNA splicing modulator | ||
| 7723 | RGD peptide | May 2022 |
| Minimal recognition sequence for integrin binding; potent integrin inhibitor | ||
| 7339 | RIPA 56 | May 2022 |
| Potent and metabolically stable RIP1 kinase inhibitor | ||
| 7684 | Rilpivirine | May 2022 |
| Non-nucleoside reverse transcriptase inhibitor | ||
| 7446 | SCOTfluor 510, fluoro | May 2022 |
| Amine-reactive fluorescent probe precursor | ||
| 7447 | SCOTfluor glucose probe 510 | Aug 2022 |
| Fluorescent glucose probe | ||
| 6529 | SGC AAK1 1N | May 2022 |
| Negative control for SGC AAK1 1 (Cat.No. 6528) | ||
| 7675 | SJ 1008030 | Jun 2022 |
| Selective JAK2 Degrader (PROTAC®) | ||
| 7542 | SJ 1008066 | Mar 2022 |
| MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction | ||
| 7720 | SJ 6986 | Jul 2022 |
| Molecular glue; induces degradation of GSPT1/2 | ||
| 7583 | SK 575 | May 2022 |
| Potent PARP1 Degrader (PROTAC®) | ||
| 7588 | SK 575-NEG | May 2022 |
| Negative control for SK 575 (Cat. No. 7583) | ||
| 7498 | SPOP-i-6lc | Mar 2022 |
| SPOP E3 ubiquitin ligase inhibitor | ||
| 7558 | SRT 1720 | Jul 2022 |
| Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis | ||
| 7554 | SSYA10-001 | Jul 2022 |
| Potent coronavirus helicase inhibitor; also inhibits human papillomavirus E6 | ||
| 7696 | Selpercatinib | May 2022 |
| Potent and selective RET inhibitor | ||
| 7712 | Semax | Jun 2022 |
| Reduces Aβ aggregation and fibrillogenesis; neuroprotective and neurotrophic peptide | ||
| 2395 | Sertraline hydrochloride | Mar 2022 |
| 5-HT reuptake inhibitor | ||
| TB1285-RMU | Staurosporine | Mar 2022 |
| Staurosporine synthesized to Ancillary Material Grade | ||
| TB6666-RMU | T3 | May 2022 |
| T3 synthesized to Ancillary Material Grade | ||
| 7665 | 5-TAMRA NHS | Aug 2022 |
| Fluorescent amine-reactive DNA and RNA probe; also stains telomeres | ||
| 7660 | TBI | Aug 2022 |
| Fluorogenic ligand for Broccoli RNA aptamer | ||
| 7742 | TFRGAP-NH2 | Aug 2022 |
| PAR3 peptide agonist | ||
| 7493 | Tasimelteon | Aug 2022 |
| Selective dual melatonin receptor (MT1/MT2) agonist | ||
| 7735 | Thalidomide 5'-amine-PEG1-amine | Jul 2022 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7736 | Thalidomide 5'-amine-PEG2-amine | Jul 2022 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7737 | Thalidomide 5'-amine-PEG3-amine | Jul 2022 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7733 | Thalidomide 5'-amine-alkylC10-amine | Jun 2022 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7557 | Thalidomide 5'-amine-alkylC8-amine | May 2022 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7122 | Thioflavin T | Apr 2022 |
| Fluorescent amyloid stain, binds to the stacked β sheets of amyloid fibrils | ||
| 7563 | Tissue Clearing Pro Reagent 1 | Jul 2022 |
| Tissue clearing reagent | ||
| 7564 | Tissue Clearing Pro Reagent 2 | Jul 2022 |
| Tissue clearing reagent | ||
| 7565 | Tissue Clearing Pro-Organoid Reagent | Jul 2022 |
| 3D cell culture clearing reagent | ||
| 7709 | Trametinib | Jul 2022 |
| Potent and selective MEK inhibitor; orally bioavailable | ||
| 7640 | Tucatinib | May 2022 |
| Potent and selective ErbB2 inhibitor | ||
| 6604 | VER 246608 | May 2022 |
| Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 /4 inhibitor | ||
| 7215 | VH 032 amide-PEG4-acid | May 2022 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7569 | Verdinexor | Aug 2022 |
| Selective exportin-1 (XPO1/CRM1) inhibitor | ||
| 7659 | Verubecestat | Apr 2022 |
| BACE1 and BACE2 inhibitor | ||
| 7710 | Vismodegib | Aug 2022 |
| Potent hedgehog pathway inhibitor | ||
| 7580 | WIC1 | Jul 2022 |
| Inhibitor of Wnt/β-catenin signaling | ||
| 6290 | WZ 4002 | Aug 2022 |
| Potent mutant-selective EGFR inhibitor | ||
| 7669 | XY-06-007 | Aug 2022 |
| Potent and selective Degrader of Brd4BD1 L94V fusion proteins | ||
| 7278 | α1A-AR Degrader 9c | May 2022 |
| Selective α1A adrenergic receptor Degrader (PROTAC®) | ||
| 7530 | dTAG-47 | May 2022 |
| Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation | ||
| 7531 | dTAG-47-NEG | May 2022 |
| Negative control for dTAG-47 (Cat. No. 7530) | ||
| 7584 | iP300v | Feb 2022 |
| Negative control for iP300w (Cat. No. 7270) | ||
| 7635 | tri-GalNAc biotin | May 2022 |
| Biotinylated ASGPR ligand for LYTAC research and development |