Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat No | Product Name / Activity | Date Added |
|---|---|---|
| 6167 | A 196 | Jul 2017 |
| Potent and selective SUV420H1/H2 inhibitor | ||
| 6165 | AC 265347 | Jul 2017 |
| CaSR biased allosteric modulator | ||
| 6193 | AM 4113 | Aug 2017 |
| Selective, high affinity CB1 antagonist | ||
| 5658 | AR-C 141990 hydrochloride | Jul 2017 |
| MCT1 inhibitor | ||
| 6084 | ASP 9521 | Sep 2017 |
| Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable | ||
| 5675 | AZ PFKFB3 26 | May 2017 |
| Potent and selective PFKFB3 inhibitor | ||
| 6060 | AZD 2461 | May 2017 |
| Potent PARP inhibitor; orally bioavailable | ||
| 6161 | Ailanthone | Apr 2017 |
| Potent inhibitor of androgen receptor (AR) | ||
| 6219 | Arformoterol tartrate | Apr 2017 |
| Long-acting β2 agonist (LABA) | ||
| 6009 | B I09 | Apr 2017 |
| IRE1 endonuclease inhibitor; cell permeable | ||
| 6116 | BHPI | Aug 2017 |
| ERα antagonist; also activates unfolded protein response; active in vivo | ||
| 6078 | BPTU | Jul 2017 |
| P2Y1 allosteric antagonist | ||
| 6282 | BRD 4770 | Jun 2017 |
| G9a inhibitor and S-adenosyl methionine mimetic; cell permeable | ||
| 6284 | BRD 73954 | Jun 2017 |
| Dual histone deacetylase (HDAC) 6/8 inhibitor | ||
| 6304 | BigLEN (mouse) | Jul 2017 |
| GPR171 agonist | ||
| 6306 | BigLEN (rat) | Jul 2017 |
| Potent GPR171 agonist | ||
| 5372 | Bioymifi | May 2017 |
| DR5 (TRAIL receptor) agonist; induces apoptosis | ||
| 6196 | Brequinar sodium | Aug 2017 |
| Potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor | ||
| 5821 | C-DIM 12 | May 2017 |
| Nurr1 activator; inhibits NF-κB-dependent gene expression | ||
| 6258 | CC 401 dihydrochloride | May 2017 |
| High affinity JNK inhibitor; also inhibits HCMV replication | ||
| 6142 | CL 075 | Sep 2017 |
| TLR8 agonist | ||
| 5963 | CMPI hydrochloride | May 2017 |
| Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs | ||
| 6174 | CVT 313 | Jun 2017 |
| cdk2 inhibitor | ||
| 6264 | Caerulein | Mar 2017 |
| CCK agonist | ||
| 5435 | Cyanine 3, SE | Mar 2017 |
| Orange fluorescent dye for labeling of amines | ||
| 5437 | Cyanine 7, SE | Mar 2017 |
| Near-infrared fluorescent dye for labeling of amines | ||
| 5921 | D9 | May 2017 |
| Potent thioredoxin reductase (TrxR) inhibitor | ||
| 6175 | DBHDA | Apr 2017 |
| Reagent for synthetic biology; converts cysteine to dehydroalanine | ||
| 6240 | DG 041 | Aug 2017 |
| Potent and selective EP3 antagonist; antiplatelet and antithrombotic | ||
| 6231 | Dacomitinib | Jul 2017 |
| Potent irreversible pan ErbB inhibitor | ||
| 6277 | 7α,25-Dihydroxycholesterol | Jun 2017 |
| Highly potent GPR183 (EBI2) agonist | ||
| 6292 | ELARR>GG | Jul 2017 |
| Negative control for ELA-32 (Cat.No.6291). | ||
| 6293 | ELA-14 (human) | Jun 2017 |
| Potent apelin (APJ) receptor agonist | ||
| 6294 | ELA-14 negative control | Jun 2017 |
| Negative control for ELA-14 (Cat.No.6293). | ||
| 6291 | ELA-32 (human) | Jul 2017 |
| Potent, high affinity apelin receptor agonist; stimulates angiogenesis | ||
| 5924 | ER 819762 | Sep 2017 |
| Potent EP4 receptor antagonist; orally bioavailable | ||
| 6234 | Entecavir | Apr 2017 |
| Potent and selective hepatitis B virus inhibitor | ||
| 6158 | (S)-Equol | May 2017 |
| Potent estrogen receptor β (ERβ) agonist; dihydrotestosterone antagonist | ||
| 6188 | Everolimus | Apr 2017 |
| mTOR inhibitor;immunosuppressant | ||
| 6253 | F 127 (20% solution in DMSO) | Apr 2017 |
| Nonionic detergent | ||
| 6237 | FPS ZM1 | Aug 2017 |
| High affinity antagonist of RAGE | ||
| 6100 | Fasentin | May 2017 |
| GLUT1/GLUT4 inhibitor; also Fas-sensitizer | ||
| 6051 | G 5555 | Sep 2017 |
| Selective high affinity group 1 PAK inhibitor | ||
| 5401 | GSK 2250665A | Aug 2017 |
| Itk inhibitor | ||
| 6128 | GSK 343 | Jun 2017 |
| Potent and selective SAM-competitive EZH2 inhibitor | ||
| 6218 | Galiellalactone | Apr 2017 |
| STAT3 inhibitor; active in vivo | ||
| 6211 | H3K27(Me) (15-34) | Apr 2017 |
| Histone H3 peptide; substrate for demethylase/methyltransferase enzymes | ||
| 6212 | H3K27(Me2) (15-34) | Apr 2017 |
| Histone H3 peptide; substrate for methyltransferase/demethylase enzymes | ||
| 6213 | H3K27(Me3) (15-34) | Apr 2017 |
| Histone H3 peptide; substrate for methyltransferase/demethylase enzymes | ||
| 6214 | H3K4(Me) (1-20) | Apr 2017 |
| Histone H3 peptide; substrate for methyltransferase/demethylase enzymes | ||
| 6215 | H3K4(Me2) (1-20) | May 2017 |
| Histone H3 peptide | ||
| 6216 | H3K4(Me3) (1-20) | Apr 2017 |
| Histone H3 peptide; substrate for methyltransferase/demethylase enzymes | ||
| 5768 | HS 38 | Jul 2017 |
| ATP-competitive inhibitor of DAPK and ZIPK | ||
| 6217 | Histone H3 (1-34) | Apr 2017 |
| Histone H3 peptide | ||
| 5741 | 25-Hydroxycholesterol | Apr 2017 |
| Antiviral; also α-crystallin (cryAB) chaperone | ||
| 6016 | IN 1130 | Jul 2017 |
| Potent and selective inhibitor of TGF-βRI | ||
| 4322 | JH 295 | May 2017 |
| Irreversible Nek2 inhibitor | ||
| 6289 | JH-II-127 | Aug 2017 |
| Potent and selective LRRK2 inhibitor | ||
| 6278 | JNJ 55511118 | Aug 2017 |
| Selective, high affinity negative modulator of AMPA receptors containing TARP-γ8 | ||
| 5865 | KLH 45 | Mar 2017 |
| Potent DDHD2 inhibitor | ||
| 6151 | LDN 212854 | Apr 2017 |
| Potent bone morphogenetic protein type I (ALK) inhibitor | ||
| 6152 | LDN 214117 | Apr 2017 |
| Potent and selective ALK2 inhibitor | ||
| 5826 | LEI 101 hydrochloride | May 2017 |
| Potent and selective CB2 partial agonist; orally biovailable | ||
| 6098 | Lalistat 1 | Aug 2017 |
| Potent and selective lysosomal acid lipase (LAL) inhibitor | ||
| 3974 | Latrunculin B | May 2017 |
| Inhibitor of actin polymerization | ||
| 6305 | Lenalidomide | Jun 2017 |
| Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase | ||
| 6265 | Lonafarnib | Jul 2017 |
| Potent farnesyl transferase inhibitor | ||
| 5103 | Lys-CoA | Jun 2017 |
| Selective p300 inhibitor | ||
| 5705 | M62812 | Aug 2017 |
| TLR-4 inhibitor | ||
| 5842 | MK 386 | May 2017 |
| Potent, selective human type 1 5α-reductase inhibitor | ||
| 5987 | (±)-ML 209 | Apr 2017 |
| RORγt inverse agonist; suppresses Th17 cell differentiation | ||
| 5700 | ML 315 hydrochloride | Apr 2017 |
| Inhibitor of Clk and DYRK kinases | ||
| 5888 | MOPSO, free acid | May 2017 |
| Buffer; working pH range in aqueous solution: 6.2-7.6 | ||
| 6299 | MS 15203 | Aug 2017 |
| Potent and selective GPR171 partial agonist | ||
| 6208 | MS 275 | Jun 2017 |
| HDAC (Class I) inhibitor | ||
| 6154 | MZ 1 | Apr 2017 |
| (+)-JQ1 based PROTAC that selectively degrades BRD4 in cells | ||
| 6285 | Megestrol Acetate | May 2017 |
| Synthetic progesterone analog | ||
| 6189 | Myricetin | Jun 2017 |
| Irreversible TrxR inhibitor | ||
| 6121 | NB-caged Tyrosine hydrochloride | May 2017 |
| ortho-nitrobenzyl caged L- tyrosine | ||
| 5150 | NCL 00017509 | May 2017 |
| Potent and reversible NIMA related kinase 2 (Nek2) inhibitor | ||
| 5956 | NF 1819 | Aug 2017 |
| Potent and selective irreversible MAGL inhibitor; membrane permeable and brain penetrant | ||
| 6045 | NITD 008 | Jul 2017 |
| Antiviral; selective flavivirus inhibitor | ||
| 6180 | NMS 873 | Apr 2017 |
| Potent and selective p97 ATPase (VCP) allosteric inhibitor | ||
| 5818 | NVP BSK 805 | Aug 2017 |
| Potent JAK2 inhibitor; orally bioavailable | ||
| 6183 | Nanchangmycin | May 2017 |
| Antiviral; active against Zika, West Nile and dengue viruses | ||
| 5976 | Ned K | Apr 2017 |
| NAADP signaling inhibitor | ||
| 6075 | Nutlin 3a | Sep 2017 |
| MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984) | ||
| 6119 | OB 24 hydrochloride | Aug 2017 |
| Potent and selective heme oxygenase 1 (HO-1) inhibitor | ||
| 6181 | OTX 015 | May 2017 |
| BET bromodomain inhibitor; orally bioavailable | ||
| 6012 | OXSI 2 | May 2017 |
| Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes | ||
| 6073 | P21d hydrochloride | Jun 2017 |
| Potent and selective Brk inhibitor | ||
| 6149 | PA Janelia Fluor® 549, SE | Apr 2017 |
| Photoactivatable cell permeable fluorescent dye; supplied as NHS ester | ||
| 6150 | PA Janelia Fluor® 646, SE | Apr 2017 |
| Photoactivatable cell permeable fluorescent dye; supplied as NHS ester | ||
| 6307 | PEN (human) | Sep 2017 |
| GPR83 agonist | ||
| 6308 | PEN (mouse) | Sep 2017 |
| GPR83 agonist | ||
| 6309 | PEN (rat) | Sep 2017 |
| GPR83 agonist | ||
| 5863 | PF 04620110 | Sep 2017 |
| Potent and selective DGAT-1 inhibitor; orally bioavailable | ||
| 6347 | PF 04628935 | Sep 2017 |
| Potent ghrelin receptor inverse agonist | ||
| 6049 | PF 04937319 | Aug 2017 |
| Glucokinase partial activator | ||
| 6345 | PF 04991532 | Sep 2017 |
| Potent hepatoselective glucokinase activator | ||
| 6346 | PF 5006739 | Sep 2017 |
| Potent CK1δ/ε inhibitor | ||
| 6221 | PKI (5-24) | Mar 2017 |
| High affinity PKA inhibitor | ||
| 6083 | PSB 12379 | Aug 2017 |
| Ecto-5'-nucleotidase (CD73) inhibitor | ||
| 6192 | PZ-II-029 | Sep 2017 |
| α6β3γ2-selective GABAA channel modulator | ||
| 6303 | Parathyroid hormone (1-34) (bovine) | Jun 2017 |
| Parathyroid hormone (PTH) receptor agonist. | ||
| 6301 | Parathyroid hormone (1-34) (rat) | Jun 2017 |
| Parathyroid hormone (PTH) receptor agonist | ||
| 6185 | Pemetrexed | Jun 2017 |
| High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICART | ||
| 6288 | Peptide YY (3-36) human | Jun 2017 |
| NPY Y2 receptor agonist | ||
| 6302 | Pomalidomide | Jun 2017 |
| Cereblon ubiquitination inhibitor; also TNF-α inhibitor and antiangiogenic | ||
| 6317 | Prasugrel | Jul 2017 |
| Irreversible P2Y12 antagonist; antiplatelet and orally active | ||
| 6048 | R-BC154 | Aug 2017 |
| High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs | ||
| 6259 | RAGE antagonist peptide | May 2017 |
| RAGE antagonist | ||
| 6168 | RI 1 | Apr 2017 |
| RAD51 recombinase inhibitor | ||
| 6190 | Retrobradykinin | Apr 2017 |
| Reverse analog of Bradykinin | ||
| 6230 | Rucaparib camsylate | Aug 2017 |
| PARP inhibitor | ||
| 6164 | SEA 0400 | Apr 2017 |
| Potent Na+/Ca2+ exchanger (NCX) inhibitor. | ||
| 5452 | SKI 178 | May 2017 |
| Non-lipid sphingosine kinase 1 (SphK1) inhibitor | ||
| 6038 | SR 10067 | Aug 2017 |
| Selective Rev-Erbα/β agonist; anxiolytic | ||
| 6271 | ST 034307 | May 2017 |
| Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo | ||
| 6036 | STK16-IN-1 | May 2017 |
| Serine/threonine protein kinase 16 (STK16) inhibitor; also inhibits PI 3Kδ, PI 3Kγ and mTOR kinases. | ||
| 5523 | TAPI 0 | Sep 2017 |
| ADAM-17 (TACE) and MMP inhibitor | ||
| 6162 | TAPI 1 | Sep 2017 |
| ADAM-17 (TACE) and MMP inhibitor | ||
| 6013 | TAPI 2 | Sep 2017 |
| ADAM-17 (TACE) and MMP inhibitor | ||
| 5729 | TASP 0390325 | Apr 2017 |
| Potent and selective V1B receptor antagonist; orally bioavailable | ||
| 6227 | TAT-Gap19 | Apr 2017 |
| Cx43 hemichannel blocker | ||
| 6105 | TC AC 28 | Mar 2017 |
| High affinity BET bromodomain ligand | ||
| 6191 | TH 1020 | Jul 2017 |
| Toll-like receptor (TLR) 5/Flagellin complex antagonist | ||
| 6194 | TM 5441 | Jun 2017 |
| Plasminogen activator inhibitor-1 (PAI-1) inhibitor | ||
| 5343 | TPPB | May 2017 |
| High affinity PKC activator; also APP modulator | ||
| 6311 | Tadalafil | May 2017 |
| Potent and highly selective PDE5 inhibitor; orally bioavailable | ||
| 6342 | Tamoxifen | Sep 2017 |
| Estrogen receptor partial agonist/antagonist | ||
| 5933 | Tocriscreen Kinase Inhibitor Toolbox I | Apr 2017 |
| A library of 80 kinase inhibitor compounds (250 μL 10 mM DMSO solutions) | ||
| 6268 | Tocriscreen Kinase Inhibitor Toolbox I & II | Apr 2017 |
| A library of 160 kinase inhibitor compounds (250 μL 10 mM DMSO solutions) | ||
| 6225 | Tocriscreen Kinase Inhibitor Toolbox II | Apr 2017 |
| A library of 80 kinase inhibitor compounds (250 μL 10 mM DMSO solutions) | ||
| 6336 | Trazodone hydrochloride | Sep 2017 |
| 5-HT2A and α1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant | ||
| 6270 | Tubastatin A hydrochloride | Jun 2017 |
| Potent HDAC6 inhibitor | ||
| 4930 | UNC 2399 | Jun 2017 |
| Biotinylated UNC 1999 (Cat.No. 4904) | ||
| 6156 | VH 298 | Apr 2017 |
| High-affinity inhibitor of VHL | ||
| 6202 | Vilazodone hydrochloride | Apr 2017 |
| Potent 5-HT1A partial agonist and SSRI; antidepressant | ||
| 6143 | WZB 117 | Aug 2017 |
| GLUT inhibitor | ||
| 6061 | XMD 8-87 | May 2017 |
| Potent Ack1/TNK2 inhibitor | ||
| 6155 | cis MZ 1 | Apr 2017 |
| Negative Control for MZ1 | ||
| 6157 | cis VH 298 | Apr 2017 |
| Negative control for VH 298 | ||
| 6327 | dBET1 | Aug 2017 |
| (+)-JQ1 based PROTAC that selectively degrades BRD4 in cells | ||
| 6286 | st-Ht31 | Jul 2017 |
| Inhibits PKA/AKAP interactions; cell permeable | ||
| 6287 | st-Ht31 P | Jul 2017 |
| Negative control for st-Ht31 (Cat. No. 6286) |