New Products

View all New Products Alphabetically

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
7376 2A3 Mar 2022
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
TB2939-RMU A 83-01 May 2022
A 83-01 synthesized to Ancillary Material Grade
7680 ABT 263 May 2022
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
6923 AMZ 30 Jun 2022
Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor
7650 AZD 2858 May 2022
Highly potent GSK-3 inhibitor; inhibits tau phosphorylation
7479 Ac4ManNAz Jul 2022
Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe
7553 Ac4ManNDAz Apr 2022
Photo-crosslinking probe for studying glycoproteins and glycolipids
7589 Adavosertib Feb 2022
Potent and selective Wee1 inhibitor
7678 5-Amino-Thalidomide Jul 2022
Cereblon ligand with amine on C5 for onward chemistry
7664 3-Azido-7-hydroxycoumarin Aug 2022
Click-reactive fluorescent dye
7483 BDY FL VH032 Mar 2022
High-affinity VHL fluorescent probe for TR-FRET and FP assays
6878 BMS 466442 May 2022
Potent and selective inhibitor of asc-1
7528 BSJ-4-116 Jul 2022
Selective CDK12 PROTAC® Degrader
7529 BSJ-4-116-NC Jul 2022
Negative control for BSJ-4-116 (Cat. No. 7528).
7686 BromoTag® AGB1 Apr 2022
Potent and selective Degrader of Brd4BD2 L387A fusion proteins (BromoTag®)
7687 BromoTag® cis-AGB1 Apr 2022
Negative control for BromoTag® AGB1 (Cat.No. 7686)
7512 3-Bromopyruvate Apr 2022
MCT1 inhibitor; also inhibits hexokinase II
7692 C26-A6 Jul 2022
Disrupts MTDH and SND1 interaction, enhances immune surveillance
7494 CIA 1 Apr 2022
COUP-TFII inhibitor
7089 CSN5i-3 Apr 2022
Potent and selective CSN5 (COP9 signalosome) inhibitor
7532 CSN5i-3-NEG Apr 2022
Negative control for CSN5i-3 (Cat. No. 7089)
7137 Cambinol May 2022
nSMase2 inhibitor
6781 Capzimin dimer Jul 2022
Selective proteasome inhibitor
7506 Click N-Acetylmuramic acid - azide Jul 2022
Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes.
7485 Covidcil-19 Apr 2022
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
7726 DMSO, Cell Cryopreserve Grade Apr 2022
Intracellular cryoprotective agent
7236 Digoxigenin Tyramide Jul 2022
Reagent used for Tyramide Signal Amplification in IHC, ICC and ISH
7714 EDA-DA May 2022
Unnatural dipeptide building block with alkyne group for functionalizing peptidoglycan
7010 EM 163 Mar 2022
TIR-TIR interaction inhibitor
6795 GeA-69 Jul 2022
Selective allosteric PARP14 inhibitor
7685 IND 1316 Jul 2022
AMPK activator
TB4439-RMU ISX 9 Mar 2022
ISX 9 synthesized to Ancillary Material Grade
7196 Indinavir sulfate Jun 2022
Potent and selective HIV-1 and HIV-2 protease inhibitor
7510 Indocyanine green Jun 2022
Near-infrared fluorescent dye
7689 (+)-JQ1 bump, acid functionalized May 2022
Functionalized BET bromodomain ligand; precursor for Tag Degraders
7682 JQAD1 Feb 2022
Potent and selective EP300 Degrader
TB6053-GMP LDN 193189 Apr 2022
LDN 193189 synthesized to cGMP guidelines
7652 Linsitinib Apr 2022
Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor
7492 Lomitapide mesylate May 2022
Potent microsomal triglyceride transfer protein (MTP) inhibitor
7695 Mpro 61 Jul 2022
Potent non-covalent inhibitor of SARS-CoV-2 main protease
7488 MRTX 849 Feb 2022
Mutation-selective inhibitor of KRASG12C
7681 Mandi Jul 2022
Highly efficient chemical inducer of proximity (CIP)
7641 Mito-HE May 2022
Fluorescent mitochondrial superoxide indicator in live cells
7586 Molnupiravir Mar 2022
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection
7716 N-methylated pomalidomide Jul 2022
Functionalized cereblon ligand for generating Degrader negative controls; also used as Pomalidomide negative control
7538 NBD-PE Jul 2022
Single tail (16:0) phospholipid derivative with a fluorophore (NBD) on the head
7301 NHS-LC-Biotin Jul 2022
Amine reactive biotinylation reagent, cell permeable
7668 Opicapone Aug 2022
COMT inhibitor
7663 Ozanimod May 2022
Potent and selective S1P1 and S1P5 agonist
7629 Panobinostat Jun 2022
Pan-histone deacetylase inhibitor
7590 Pexidartinib Apr 2022
Potent CSF-1R inhibitor
7392 5-Ph-IAA May 2022
Selective and potent TAG Degrader for auxin-inducible degron 2 system
7201 Phalloidin-Janelia Fluor® 646 Mar 2022
Red fluorescent F-actin probe
7670 Phenyl-glutarimide 4'-oxyacetic acid Jun 2022
Functionalized cereblon ligand for PROTAC development
7362 Phototrexate Mar 2022
Photoswitchable inhibitor of human dihydrofolate reductase
7667 Pimavanserin Mar 2022
Selective 5-HT2A inverse agonist
7711 Polybrene Jul 2022
Viral transduction enhancer
7732 Pomalidomide 4'-alkylC10-amine Jul 2022
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7630 Pridopidine Mar 2022
Highly selective σ1 agonist
7701 RAGE 229 Jun 2022
ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice
7679 RECTAS May 2022
IKBKAP pre-mRNA splicing modulator
7723 RGD peptide May 2022
Minimal recognition sequence for integrin binding; potent integrin inhibitor
7339 RIPA 56 May 2022
Potent and metabolically stable RIP1 kinase inhibitor
7684 Rilpivirine May 2022
Non-nucleoside reverse transcriptase inhibitor
7446 SCOTfluor 510, fluoro May 2022
Amine-reactive fluorescent probe precursor
7447 SCOTfluor glucose probe 510 Aug 2022
Fluorescent glucose probe
6529 SGC AAK1 1N May 2022
Negative control for SGC AAK1 1 (Cat.No. 6528)
7675 SJ 1008030 Jun 2022
Selective JAK2 Degrader (PROTAC®)
7542 SJ 1008066 Mar 2022
MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction
7720 SJ 6986 Jul 2022
Molecular glue; induces degradation of GSPT1/2
7583 SK 575 May 2022
Potent PARP1 Degrader (PROTAC®)
7588 SK 575-NEG May 2022
Negative control for SK 575 (Cat. No. 7583)
7498 SPOP-i-6lc Mar 2022
SPOP E3 ubiquitin ligase inhibitor
7558 SRT 1720 Jul 2022
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
7554 SSYA10-001 Jul 2022
Potent coronavirus helicase inhibitor; also inhibits human papillomavirus E6
7696 Selpercatinib May 2022
Potent and selective RET inhibitor
7712 Semax Jun 2022
Reduces Aβ aggregation and fibrillogenesis; neuroprotective and neurotrophic peptide
2395 Sertraline hydrochloride Mar 2022
5-HT reuptake inhibitor
TB1285-RMU Staurosporine Mar 2022
Staurosporine synthesized to Ancillary Material Grade
TB6666-RMU T3 May 2022
T3 synthesized to Ancillary Material Grade
7665 5-TAMRA NHS Aug 2022
Fluorescent amine-reactive DNA and RNA probe; also stains telomeres
7660 TBI Aug 2022
Fluorogenic ligand for Broccoli RNA aptamer
7742 TFRGAP-NH2 Aug 2022
PAR3 peptide agonist
7493 Tasimelteon Aug 2022
Selective dual melatonin receptor (MT1/MT2) agonist
7735 Thalidomide 5'-amine-PEG1-amine Jul 2022
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7736 Thalidomide 5'-amine-PEG2-amine Jul 2022
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7737 Thalidomide 5'-amine-PEG3-amine Jul 2022
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7733 Thalidomide 5'-amine-alkylC10-amine Jun 2022
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7557 Thalidomide 5'-amine-alkylC8-amine May 2022
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7122 Thioflavin T Apr 2022
Fluorescent amyloid stain, binds to the stacked β sheets of amyloid fibrils
7563 Tissue Clearing Pro Reagent 1 Jul 2022
Tissue clearing reagent
7564 Tissue Clearing Pro Reagent 2 Jul 2022
Tissue clearing reagent
7565 Tissue Clearing Pro-Organoid Reagent Jul 2022
3D cell culture clearing reagent
7709 Trametinib Jul 2022
Potent and selective MEK inhibitor; orally bioavailable
7640 Tucatinib May 2022
Potent and selective ErbB2 inhibitor
6604 VER 246608 May 2022
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 /4 inhibitor
7215 VH 032 amide-PEG4-acid May 2022
VHL ligand with PEG linker and terminal acid for onward chemistry
7569 Verdinexor Aug 2022
Selective exportin-1 (XPO1/CRM1) inhibitor
7659 Verubecestat Apr 2022
BACE1 and BACE2 inhibitor
7710 Vismodegib Aug 2022
Potent hedgehog pathway inhibitor
7580 WIC1 Jul 2022
Inhibitor of Wnt/β-catenin signaling
6290 WZ 4002 Aug 2022
Potent mutant-selective EGFR inhibitor
7669 XY-06-007 Aug 2022
Potent and selective Degrader of Brd4BD1 L94V fusion proteins
7278 α1A-AR Degrader 9c May 2022
Selective α1A adrenergic receptor Degrader (PROTAC®)
7530 dTAG-47 May 2022
Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
7531 dTAG-47-NEG May 2022
Negative control for dTAG-47 (Cat. No. 7530)
7584 iP300v Feb 2022
Negative control for iP300w (Cat. No. 7270)
7635 tri-GalNAc biotin May 2022
Biotinylated ASGPR ligand for LYTAC research and development