New ProductsView all New Products Alphabetically
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| TB5758-RMU | AGN 193109 | Aug 2021 |
| AGN 193109 synthesized to Ancillary Material Grade | ||
| 7135 | AKOS 022 | May 2021 |
| Voltage-dependent anion channel (VDAC) inhibitor | ||
| 5985 | AKT Inhibitor IV | May 2021 |
| Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates | ||
| TB0760-RMU | AM 580 | Aug 2021 |
| AM 580 synthesized to Ancillary Material Grade | ||
| 7242 | Ac-FLTD-CMK | Sep 2021 |
| Potent and selective inhibitor of caspases 1, 5 and 4 | ||
| 6141 | BI-6901 | Sep 2021 |
| Potent and selective CCR10 antagonist | ||
| 7153 | BRD 0539 | Jul 2021 |
| Cell permeable and reversible Cas9 inhibitor | ||
| 6977 | Bobcat339 | Jul 2021 |
| Ten-eleven translocation methylcytosine dioxygenase (TET) inhibitor | ||
| 7379 | CB 5083 | Oct 2021 |
| Potent p97 ATPase inhibitor | ||
| 7425 | CG 428 | Aug 2021 |
| Potent tropomyosin receptor kinase (TRK) degrader | ||
| 7426 | CG 428-Neg | Aug 2021 |
| Negative control for CG 428 (Cat. No. 7425) | ||
| 7427 | CG 858 | Jul 2021 |
| Selective BRAF-V600E protein Degrader (uSMITE™) | ||
| 7428 | CG 858-Neg | Jul 2021 |
| Negative control for CG 858 (Cat. No. 7427) | ||
| 7139 | CeMMEC1 | Sep 2021 |
| TAF1 inhibitor | ||
| 7431 | Cyanine 5.5, SE | Oct 2021 |
| Far red fluorescent dye for the labeling of amines; supplied as NHS ester | ||
| 7414 | DSRM-3716 | Jun 2021 |
| Potent and reversible SARM1 NAD hydrolase inhibitor | ||
| 7305 | Defactinib | Sep 2021 |
| Potent and selective FAK and Pyk2 inhibitor | ||
| 7324 | Di 4 ANEPPS | Jun 2021 |
| Voltage-sensitive probe; used to detect changes in membrane potential in electrophysiology protocols | ||
| 7336 | Dinaciclib | Jun 2021 |
| Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9 | ||
| 7424 | EMI 48 | Oct 2021 |
| Inhibitor of EGFR mutants | ||
| 7462 | ET 18-OCH3 | Jul 2021 |
| Selective PI-PLC inhibitor, also PAF receptor agonist | ||
| 7342 | Emetine dihydrochloride | May 2021 |
| RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika | ||
| 7194 | Erlotinib Hydrochloride | Aug 2021 |
| Potent, reversible EGFR tyrosine kinase inhibitor | ||
| 7452 | FAM-DEALAHypYIPMDDDFQLRSF | Jun 2021 |
| Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity | ||
| 7306 | FC 11 | May 2021 |
| Highly potent focal adhesion kinase (FAK) Degrader (PROTAC®) | ||
| 7373 | FNIR-Tag, NHS | Sep 2021 |
| Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester | ||
| TB1099-RMU | Forskolin | Sep 2021 |
| Forskolin synthesized to Ancillary Material Grade | ||
| 7445 | GPR52 Comp-43 | Oct 2021 |
| GPR52 receptor antagonist | ||
| 6848 | GSK 2795039 | Jun 2021 |
| NADPH oxidase 2 (NOX2) inhibitor | ||
| 6497 | GSK 2833503A | Aug 2021 |
| Potent and selective TRPC6 and TRPC3 antagonist | ||
| 7030 | GW 280264X | Jul 2021 |
| Potent ADAM10 and ADAM17 inhibitor | ||
| 7229 | Galidesivir dihydrochloride | Apr 2021 |
| Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral | ||
| TB3000-RMU | Gefitinib | Aug 2021 |
| Iressa synthesized to Ancillary Material Grade | ||
| 7313 | Hoechst Janelia Fluor® 526 | Jul 2021 |
| Fluorogenic, green-emitting DNA probe | ||
| 6804 | Hoechst Janelia Fluor® 646 | Sep 2021 |
| Fluorogenic, red-emitting DNA probe | ||
| 7304 | JH-XI-10-02 | Sep 2021 |
| CDK8 Degrader (PROTAC®) | ||
| 4327 | JW 480 | Jul 2021 |
| Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1) | ||
| 5114 | K34c | Sep 2021 |
| Potent and selective α5β1 integrin inhibitor | ||
| 6738 | KT 182 | May 2021 |
| Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor | ||
| 7419 | Kyoto Probe-1 | Aug 2021 |
| Fluorescent probe that selectively identifies undifferentiated iPS/ES cells | ||
| 7420 | LC 2 | Aug 2021 |
| Selective KRAS PROTAC® | ||
| 7421 | LC 2 Epimer | Sep 2021 |
| Negative control for LC 2 (Cat. No. 7420) | ||
| TB6053-RMU | LDN 193189 | Aug 2021 |
| LDN 193189 synthesized to Ancillary Material Grade | ||
| 7407 | LEI 401 | Jun 2021 |
| High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor | ||
| 7275 | Laurdan | May 2021 |
| Polarity sensitive lipid membrane fluorescent probe; used to imaging lipid rafts | ||
| 7513 | Lenalidomide 4'-PEG1-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7514 | Lenalidomide 4'-PEG2-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7516 | Lenalidomide 4'-alkylC3-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7517 | Lenalidomide 4'-alkylC5-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7472 | Lenalidomide 5'-piperazine | Oct 2021 |
| Cereblon ligand with terminal piperazine for onward chemistry | ||
| 7473 | Lenalidomide 5'-piperazine-4-methylpiperidine | Oct 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry | ||
| 4894 | ML 299 | Sep 2021 |
| Potent inhibitor of PLD1 and PLD2; CNS penetrant | ||
| 3345 | MLN 4760 | Aug 2021 |
| Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor | ||
| 6871 | MO-I-500 | May 2021 |
| FTO inhibitor; anticonvulsant | ||
| 7320 | Methoxyluteolin | Aug 2021 |
| Inhibitor of pro-inflammatory mediator release from mast cells | ||
| 7371 | Neratinib | Aug 2021 |
| Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor | ||
| 6018 | Nicotinamide Riboside | Jul 2021 |
| NAD+ precursor; substrate for nicotinamide riboside kinases | ||
| 7387 | Nile Red | May 2021 |
| Fluorogenic lipid membrane dye | ||
| 7391 | O-Propargyl-puromycin | Jun 2021 |
| Puromycin analog for labeling newly synthesized proteins; is incorporated into nascent polypeptides | ||
| 7408 | OGDA | Sep 2021 |
| Green fluorescent D-amino acid; compatible with STED microscopy | ||
| 7410 | PARPYnD | Oct 2021 |
| PARP inhibitor; photoaffinity probe | ||
| 7218 | PZM21 | Apr 2021 |
| Selective μ receptor agonist | ||
| 7314 | Pepstatin A Janelia Fluor® 526 | May 2021 |
| Fluorogenic green-emitting lysosome tracker and stain | ||
| 7434 | Pomalidomide 4'-PEG1-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7307 | Pomalidomide 4'-PEG2-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7435 | Pomalidomide 4'-PEG3-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7436 | Pomalidomide 4'-PEG4-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7437 | Pomalidomide 4'-PEG5-azide | Jun 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7438 | Pomalidomide 4'-PEG6-azide | Jun 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7439 | Pomalidomide 4'-alkylC2-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7440 | Pomalidomide 4'-alkylC3-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7441 | Pomalidomide 4'-alkylC4-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7442 | Pomalidomide 4'-alkylC5-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7443 | Pomalidomide 4'-alkylC6-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7470 | Pomalidomide 5'-fluoro-6'-piperazine | Jul 2021 |
| Cereblon ligand with terminal piperazine for onward chemistry | ||
| 7471 | Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine | Jul 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry | ||
| 7468 | Pomalidomide 5'-piperazine | Jul 2021 |
| Cereblon ligand with terminal piperazine for onward chemistry | ||
| 7469 | Pomalidomide 5'-piperazine-4-methylpiperidine | Jul 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry | ||
| 7321 | Pritelivir | Sep 2021 |
| Potent and selective herpes simplex virus (HSV) helicase primase inhibitor | ||
| 6862 | Psoralen-triethylene glycol azide | Sep 2021 |
| RNA conformation probe; reagent for COMRADES RNA platform | ||
| 6941 | Pyr 10 | Jun 2021 |
| Selective TRPC3 inhibitor | ||
| 7129 | RA 2 | May 2021 |
| Potent negative modulator of KCa2.3 and KCa3.1 channels | ||
| 7375 | RO 8191 | Aug 2021 |
| IFNα receptor 2 agonist | ||
| 6687 | 1R,3R-RSL3 | Sep 2021 |
| Negative control for 1S,3R-RSL3 (Cat. No. 6118) | ||
| 7406 | Rf470DL | Sep 2021 |
| Blue rotor-fluorogenic fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 7486 | Roxadustat | Aug 2021 |
| HIF-PH inhibitor; erythropoietic | ||
| 7450 | SGC CK2-1 | Sep 2021 |
| Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2 | ||
| 7460 | SGC SMARCA-BRDVIII | Sep 2021 |
| Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor | ||
| 7432 | SIM1 | Sep 2021 |
| Potent and selective trivalent BET Bromodomain Degrader (PROTAC®) | ||
| 7463 | SJF 0628 | Jul 2021 |
| Potent BRAF PROTAC® | ||
| 7464 | SJF 0661 | Jul 2021 |
| Negative control for SJF 0628 (Cat. No. 7463) | ||
| 7295 | SMCy 5.5 | May 2021 |
| Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy | ||
| 7341 | STX 64 | Oct 2021 |
| Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II | ||
| 7086 | StemRegenin 1 | Sep 2021 |
| Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment | ||
| 7054 | T4 | Jul 2021 |
| Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3 | ||
| 6498 | TASP 0277308 | Sep 2021 |
| Potent and selective S1P1 receptor antagonist; inhibits angiogenesis | ||
| 7489 | TCH-165 | Sep 2021 |
| Enhancer of 20S proteasome assembly and 20S-mediated protein degradation | ||
| 7315 | Taxol Janelia Fluor® 526 | May 2021 |
| Green fluorescent taxol derivative; probe for microtubule staining | ||
| 7518 | Thalidomide 4'-ether-PEG1-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7519 | Thalidomide 4'-ether-PEG2-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7520 | Thalidomide 4'-ether-PEG3-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7521 | Thalidomide 4'-ether-alkylC3-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7522 | Thalidomide 4'-ether-alkylC5-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7403 | Thalidomide 4'-ether-alkylC8-amine | May 2021 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7214 | VH 032 amide-PEG2-acid | Sep 2021 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7404 | VH 032 amide-alkylC9-acid | May 2021 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7057 | VU 0071063 | Sep 2021 |
| Selective activator of SUR1 Kir6.2 channels | ||
| 7309 | Vemurafenib | Sep 2021 |
| Potent BRAF and CRAF inhibitor | ||
| 7055 | WS 383 | May 2021 |
| Potent, selective and reversible DCN1-UBC12 interaction inhibitor | ||
| 7157 | YKL 5-124 | Sep 2021 |
| Potent and selective CDK7 inhibitor; induces cell cycle arrest | ||
| 7240 | ZNL 02-096 | May 2021 |
| Potent and selective Wee1 Degrader (PROTAC®) | ||
| 7458 | iBET-BD2 | Sep 2021 |
| Potent and selective pan-BD2 inhibitor; orally bioavailable | ||
| 7401 | tri-GalNAc COOH | Jun 2021 |
| Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry |