New Products

View all New Products Alphabetically

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat No Product Name / Activity Date Added
6167 A 196 Jul 2017
Potent and selective SUV420H1/H2 inhibitor
6165 AC 265347 Jul 2017
CaSR biased allosteric modulator
5914 AM 0902 Oct 2017
Potent and selective TRPA1 antagonist
6193 AM 4113 Aug 2017
Selective, high affinity CB1 antagonist
6163 AR 420626 Oct 2017
FFA3 agonist
5658 AR-C 141990 hydrochloride Jul 2017
MCT1 inhibitor
6084 ASP 9521 Sep 2017
Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable
6310 AZD 1208 Oct 2017
Potent pan Pim kinase inhibitor
6332 Atosiban Nov 2017
Potent oxytocin receptor antagonist
6116 BHPI Aug 2017
ERα antagonist; also activates unfolded protein response; active in vivo
6078 BPTU Jul 2017
P2Y1 allosteric antagonist
6282 BRD 4770 Jun 2017
G9a inhibitor and S-adenosyl methionine mimetic; cell permeable
6284 BRD 73954 Jun 2017
Dual histone deacetylase (HDAC) 6/8 inhibitor
6304 BigLEN (mouse) Jul 2017
GPR171 agonist
6306 BigLEN (rat) Jul 2017
Potent GPR171 agonist
6196 Brequinar sodium Aug 2017
Potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor
6035 (S)-C33 Oct 2017
Potent PDE9 inhibitor
6258 CC 401 dihydrochloride May 2017
High affinity JNK inhibitor; also inhibits HCMV replication
6103 CD133-A15, 5'-DY647 Oct 2017
High affinity fluorescently tagged aptamer for CD133 (AC133 epitope)
6104 CD133-B19, 5'-DY647 Oct 2017
High affinity fluorescently tagged aptamer for CD133 (extracellular domain epitope)
5883 CHES Nov 2017
Buffering agent
6142 CL 075 Sep 2017
TLR8 agonist
6174 CVT 313 Jun 2017
cdk2 inhibitor
6357 Ciclesonide Nov 2017
Glucocorticoid antiasthmatic prodrug
6329 Clozapine N-oxide dihydrochloride Sep 2017
Activator of muscarinic DREADDs
6240 DG 041 Aug 2017
Potent and selective EP3 antagonist; antiplatelet and antithrombotic
5884 DIPSO Nov 2017
Buffering agents
6231 Dacomitinib Jul 2017
Potent irreversible pan ErbB inhibitor
6277 7α,25-Dihydroxycholesterol Jun 2017
Highly potent GPR183 (EBI2) agonist
6292 ELARR>GG Jul 2017
Negative control for ELA-32 (Cat.No.6291).
6293 ELA-14 (human) Jun 2017
Potent apelin (APJ) receptor agonist
6294 ELA-14 negative control Jun 2017
Negative control for ELA-14 (Cat.No.6293).
6291 ELA-32 (human) Jul 2017
Potent, high affinity apelin receptor agonist; stimulates angiogenesis
5924 ER 819762 Sep 2017
Potent EP4 receptor antagonist; orally bioavailable
6102 Ep23, 5'-DY647 Oct 2017
High affinity fluorescently tagged aptamer for EpCam
6237 FPS ZM1 Aug 2017
High affinity antagonist of RAGE
6051 G 5555 Sep 2017
High affinity group 1 PAK inhibitor
5401 GSK 2250665A Aug 2017
Itk inhibitor
6128 GSK 343 Jun 2017
Potent and selective SAM-competitive EZH2 inhibitor
5885 HEPPS Oct 2017
Used as a buffering agent
5886 HEPPSO Nov 2017
Buffering agent
5768 HS 38 Jul 2017
ATP-competitive inhibitor of DAPK and ZIPK
6226 IC 87201 Oct 2017
nNOS-PSD95 protein-protein interaction inhibitor; also antinociceptive and antidepressant
6016 IN 1130 Jul 2017
Potent and selective inhibitor of TGF-βRI
6172 INF 4E Oct 2017
Caspase-1 and NLRP3 inflammasome inhibitor
4322 JH 295 May 2017
Irreversible Nek2 inhibitor
6289 JH-II-127 Aug 2017
Potent and selective LRRK2 inhibitor
6278 JNJ 55511118 Aug 2017
Selective, high affinity negative modulator of AMPA receptors containing TARP-γ8
6098 Lalistat 1 Aug 2017
Potent and selective lysosomal acid lipase (LAL) inhibitor
6099 Lalistat 2 Sep 2017
Selective lysosomal acid lipase inhibitor
6305 Lenalidomide Jun 2017
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
6265 Lonafarnib Jul 2017
Potent farnesyl transferase inhibitor
5103 Lys-CoA Jun 2017
Selective p300 inhibitor
5705 M62812 Aug 2017
TLR-4 inhibitor
5875 MES sodium salt Nov 2017
Buffering agent
5887 MES, free acid Oct 2017
Commonly used buffer
5733 ML 311 Nov 2017
Inhibits Mcl-1-BIM interaction
5877 MOPS, sodium salt Oct 2017
Used as a buffering agent
6299 MS 15203 Aug 2017
Potent and selective GPR171 partial agonist
6298 MS 21570 Nov 2017
GPR171 antagonist
6208 MS 275 Jun 2017
HDAC (Class I) inhibitor
6189 Myricetin Jun 2017
Irreversible TrxR inhibitor
5956 NF 1819 Aug 2017
Potent and selective irreversible MAGL inhibitor; membrane permeable and brain penetrant
6045 NITD 008 Jul 2017
Antiviral; selective flavivirus inhibitor
5818 NVP BSK 805 Aug 2017
Potent JAK2 inhibitor; orally bioavailable
6132 NVS PAK1 1 Oct 2017
Potent and selective PAK1 inhibitor
6339 Netilmicin sulfate Oct 2017
Inhibits HIV-1 replication; also semisynthetic aminoglycoside antibiotic
6370 Nor NOHA monoacetate Sep 2017
Arginase inhibitor
6075 Nutlin 3a Sep 2017
MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)
6119 OB 24 hydrochloride Aug 2017
Potent and selective heme oxygenase 1 (HO-1) inhibitor
6181 OTX 015 May 2017
BET bromodomain inhibitor; orally bioavailable
6012 OXSI 2 May 2017
Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes
6073 P21d hydrochloride Jun 2017
Potent and selective Brk inhibitor
6307 PEN (human) Sep 2017
GPR83 agonist
6308 PEN (mouse) Sep 2017
GPR83 agonist
6309 PEN (rat) Sep 2017
GPR83 agonist
6374 PF 04457845 Nov 2017
Potent and selective irreversible FAAH inhibitor
5863 PF 04620110 Sep 2017
Potent and selective DGAT-1 inhibitor; orally bioavailable
6347 PF 04628935 Sep 2017
Potent ghrelin receptor inverse agonist
6024 PF 04671536 hydrochloride Nov 2017
Potent and selective PDE8B/8A inhibitor
6049 PF 04937319 Aug 2017
Glucokinase partial activator
6345 PF 04991532 Sep 2017
Potent hepatoselective glucokinase activator
6348 PF 06424439 Oct 2017
Potent and selective DGAT2 inhibitor
6373 PF 06650833 Nov 2017
Potent and selective IRAK4 inhibitor
6346 PF 5006739 Sep 2017
Potent CK1δ/ε inhibitor
5889 PIPES, free acid Oct 2017
Commonly used buffer
6083 PSB 12379 Aug 2017
Ecto-5'-nucleotidase (CD73) inhibitor
6192 PZ-II-029 Sep 2017
α6β3γ2-selective GABAA channel modulator
6303 Parathyroid hormone (1-34) (bovine) Jun 2017
Parathyroid hormone (PTH) receptor agonist.
6301 Parathyroid hormone (1-34) (rat) Jun 2017
Parathyroid hormone (PTH) receptor agonist
6185 Pemetrexed Jun 2017
High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICART
6288 Peptide YY (3-36) human Jun 2017
NPY Y2 receptor agonist
6385 Phenanthroline Nov 2017
Enhances hPSC differentiation into cranial placode cells
6333 Phosphoramidon disodium salt Nov 2017
Neutral endopeptidase and endothelin converting enzyme inhibitor
6182 Pimonidazole Nov 2017
Hypoxia detection reagent
6302 Pomalidomide Jun 2017
Cereblon ubiquitination inhibitor; also TNF-α inhibitor and antiangiogenic
6317 Prasugrel Jul 2017
Irreversible P2Y12 antagonist; antiplatelet and orally active
6048 R-BC154 Aug 2017
High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs
6343 Rosuvastatin calcium Nov 2017
Potent HMG-CoA reductase inhibitor
6230 Rucaparib camsylate Aug 2017
PARP inhibitor
6414 Rupintrivir Nov 2017
Potent and selective irreversible human rhinovirus 3C protease inhibitor
5831 SAR 7334 Sep 2017
Potent TRPC6 inhibitor
6038 SR 10067 Aug 2017
Selective Rev-Erbα/β agonist; anxiolytic
6195 SSR 149415 Nov 2017
Potent and selective vasopressin V1B antagonist
6271 ST 034307 May 2017
Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
6337 Sulopenem Nov 2017
Penem antibiotic
5523 TAPI 0 Sep 2017
ADAM-17 (TACE) and MMP inhibitor
6162 TAPI 1 Sep 2017
ADAM-17 (TACE) and MMP inhibitor
6013 TAPI 2 Sep 2017
ADAM-17 (TACE) and MMP inhibitor
5891 TES, free acid Nov 2017
Buffering agent
6191 TH 1020 Jul 2017
Toll-like receptor (TLR) 5/Flagellin complex antagonist
6194 TM 5441 Jun 2017
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
5343 TPPB May 2017
High affinity PKC activator; also APP modulator
6311 Tadalafil May 2017
Potent and highly selective PDE5 inhibitor; orally bioavailable
6342 Tamoxifen Sep 2017
Estrogen receptor partial agonist/antagonist
6336 Trazodone hydrochloride Sep 2017
5-HT2A and α1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant
6270 Tubastatin A hydrochloride Jun 2017
Potent HDAC6 inhibitor
4930 UNC 2399 Jun 2017
Biotinylated UNC 1999 (Cat.No. 4904)
6143 WZB 117 Aug 2017
GLUT inhibitor
6327 dBET1 Aug 2017
(+)-JQ1 based PROTAC that selectively degrades BET bromodomains in cells
6286 st-Ht31 Jul 2017
Inhibits PKA/AKAP interactions; cell permeable
6287 st-Ht31 P Jul 2017
Negative control for st-Ht31 (Cat. No. 6286)