Glutamate (Metabotropic) Group I Receptor Modulators
| Cat. No. | Product Name / Activity |
|---|---|
| 4416 | ADX 10059 hydrochloride |
| Negative allosteric modulator of mGlu5 receptors | |
| 3235 | CDPPB |
| Positive allosteric modulator of mGlu5 receptors | |
| 2386 | Fenobam |
| Potent and selective mGlu5 negative allosteric modulator (NAM) | |
| 6859 | FITM |
| Potent and selective negative allosteric modulator of mGlu1 receptors | |
| 5000 | FTIDC |
| Potent and selective negative allosteric modulator of mGlu1 receptors; also mGlu1 inverse agonist | |
| 5275 | LSN 2463359 |
| Potent and selective positive allosteric modulator of mGlu5 receptors | |
| 4347 | Ro 67-4853 |
| Positive allosteric modulator of group I mGlu receptors | |
| 4346 | Ro 67-7476 |
| Positive allosteric modulator of mGlu1 receptors | |
| 4323 | VU 0360172 hydrochloride |
| Positive allosteric modulator of mGlu5 receptors | |
| 5693 | VU 0409551 |
| Selective positive allosteric modulator of mGlu5 receptors; brain penetrant and orally bioavailable | |
| 6895 | VU 0424465 |
| Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity | |
| 5379 | VU 0469650 hydrochloride |
| Potent and selective negative allosteric modulator of mGlu1 receptors |
Our Metabotropic Glutamate Receptor review gives an overview of the pharmacological ligands used to study the mGlu receptors.
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