DNA Topoisomerase Inhibitors

Cat. No. Product Name / Activity
4219 Banoxantrone dihydrochloride
Prodrug topoisomerase II inhibitor
1100 Camptothecin
DNA topoisomerase inhibitor
3203 Celastrol
Topoisomerase II inhibitor
5125 CKD 602
Topoisomerase I inhibitor
2688 CPT 11
DNA topoisomerase I inhibitor; antitumor
3857 Dexrazoxane hydrochloride
Topoisomerase II inhibitor
2252 Doxorubicin hydrochloride
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
3357 Ellipticine
Antitumor and intercalating agent; inhibits DNA topoisomerase II
3260 Epirubicin hydrochloride
Inhibits DNA topoisomerase II
1226 Etoposide
Topoisomerase II inhibitor
3849 Gatifloxacin
Antibiotic; inhibits bacterial type II topoisomerase
1293 β-Lapachone
DNA topoisomerase I inhibitor
4250 Mitoxantrone dihydrochloride
Topoisomerase II inhibitor; immunosuppressive and antineoplastic agent
3135 NU 2058
Topoisomerase II inhibitor. Also inhibits cdk1 and cdk2
2684 SN 38
DNA topoisomerase I inhibitor; antitumor
4562 Topotecan hydrochloride
DNA topoisomerase I inhibitor; Camptothecin (Cat. No. 1100) analog
3863 Trovafloxacin mesylate
Antibiotic; inhibits bacterial DNA topoisomerase IV and DNA gyrase