DNA Topoisomerase Inhibitors

Cat. No. Product Name / Activity
4219 Banoxantrone dihydrochloride
Prodrug topoisomerase II inhibitor
1100 Camptothecin
DNA topoisomerase inhibitor
3203 Celastrol
Topoisomerase II inhibitor
2688 CPT 11
DNA topoisomerase I inhibitor; antitumor
1467 Daunorubicin hydrochloride
DNA topoisomerase II inhibitor
3857 Dexrazoxane hydrochloride
Topoisomerase II inhibitor
2252 Doxorubicin hydrochloride
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
3260 Epirubicin hydrochloride
Inhibits DNA topoisomerase II
1226 Etoposide
Topoisomerase II inhibitor
1293 β-Lapachone
DNA topoisomerase I inhibitor
4250 Mitoxantrone dihydrochloride
Topoisomerase II inhibitor; immunosuppressive and antineoplastic agent
3135 NU 2058
Topoisomerase II inhibitor. Also inhibits cdk1 and cdk2
2684 SN 38
DNA topoisomerase I inhibitor; antitumor
6975 Teniposide
DNA topoisomerase II inhibitor; viral transduction enhancer
4562 Topotecan hydrochloride
DNA topoisomerase I inhibitor; Camptothecin (Cat. No. 1100) analog
3863 Trovafloxacin mesylate
Antibiotic; inhibits bacterial DNA topoisomerase IV and DNA gyrase