JAK-STAT Signaling Pathway

Pathway Key Download PDF

The JAK-STAT signaling pathway has several roles, including the control of cell proliferation and hematopoiesis. In addition to their action on STATs, JAKs activate additional signaling molecules which leads to crossover with other pathways such as MAPK and Akt.

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Signaling Pathway Key
Stimulates
Stimulates
Inhibits
Inhibits
Multistep Activation
Multistep Activation
Kinase
Kinase
Enzyme-linked Receptor
Enzyme-linked Receptor
Transcription Factor
Transcription Factor
Other Protein
Other Protein
Prosurvival
Prosurvival