Other ER Stress/UPR


Cat. No. Product Name / Activity
5796 Azoramide
Unfolded protein response (UPR) modulator


Cat. No. Product Name / Activity
5141 AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
4417 DBeQ
Selective and reversible p97 ATPase inhibitor
3922 Eeyarestatin I
Potent inhibitor of ER-associated protein degradation and translocation
5284 trans-ISRIB
Integrated stress response (ISR) inhibitor
5153 ML 240
ATP-competitive inhibitor of p97 ATPase
6180 NMS 873
Potent and selective p97 ATPase (VCP) allosteric inhibitor
2347 Salubrinal
Selective inhibitor of eIF2a dephosphorylation
4825 TC ASK 10
Potent and selective ASK1 inhibitor; orally bioavailable
4686 Xanthohumol
p97 ATPase (VCP) inhibitor


Cat. No. Product Name / Activity
5869 CDN 1163
SERCA2 allosteric activator


Cat. No. Product Name / Activity
6759 AA 147
ER proteostasis regulator
1072 AGN 192403 hydrochloride
Binds TMED9 cargo receptor; releases mutant MUC-1 from vesicles and promotes trafficking to lysosome fro degradation
6116 BHPI
Activates unfolded protein response; also ERα antagonist
5375 BIX
BiP (Hsp70-5) ER chaperone inducer