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|Cat. No.||Product Name / Activity|
|Suppresses differentiation of adipocytes; Foxo1 inhibitor|
|Represses pluripotency genes in mouse embryonic stem cells; histone acetyltransferase (HAT) inhibitor|
|AhR antagonist; attenuates Th17 differentiation of naive CD4 T cells|
|Promotes differentiation of oligodendrocytes from progenitors; H1 antagonist|
|Selective PSC eliminating agent|
|Inhibits transcriptional activity of pluripotency markers; HIF α-subunit inhibitor|
|Promotes differentiation of oligodendrocytes from progenitors; Cytochrome P450c17 inhibitor|
|Promotes differentiation of oligodendrocytes from progenitors; antifungal agent|
|Promotes myoblast differentiation; enhances proliferation and regenerative capacity of muSCs|
|Promotes differentiation of adipocytes; also potent and selective PPARγ agonist|
|Promotes stem cell proliferation, differentiation and sheet formation|
|Selective Smad3 inhibitor; inhibits TGF-β-induced myofibroblast differentiation|
|Promotes differentiation of oligodendroglial precursor cells; thyroid hormone|
|Induces differentiation of hESC to pancreatic progenitors; also high affinity PKC activator and APP modulator|
Tocris offers the following scientific literature for Other Differentiation Products to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.