Hedgehog Signaling Inhibitors

Cat. No. Product Name / Activity
1639 AY 9944 dihydrochloride
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase
4529 Ciliobrevin A
Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein
1623 Cyclopamine
Inhibitor of Hedgehog (Hh) signaling
6896 Dynapyrazole A
Hedgehog signaling inhibitor; dynein inhibitor
6526 Dynarrestin
Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein
3191 GANT 61
GLI antagonist; inhibits Hedgehog (Hh) signaling
3839 HPI 1
Inhibits Hedgehog signaling
5554 IHR 1
Potent Smo antagonist
5561 IHR-Cy3
Potent fluorescent Smo antagonist
6538 PF 04449913 maleate
Potent Smo antagonist
5262 PF 5274857 hydrochloride
High affinity and selective Smoothened (Smo) receptor antagonist
1974 SANT-1
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
1638 U 18666A
Inhibitor of Hedgehog (Hh) signaling. Also inhibits cholesterol synthesis