Ferroptosis Activators
| Cat. No. | Product Name / Activity |
|---|---|
| 5449 | Erastin |
| Ferroptosis activator; also mitochondrial VDAC modulator | |
| 6280 | FIN 56 |
| Ferroptosis activator | |
| 7941 | FSEN 1 |
| Induces ferroptosis; inhibits FSP1 | |
| 0218 | L-Glutamic acid |
| Induces ferroptosis; endogenous, non-selective agonist | |
| 7162 | iFSP1 |
| Ferroptosis inducer; inhibits ferroptosis suppressor protein 1 (FSP1) | |
| 6954 | L-Buthionine sulfoximine |
| Induces ferroptosis by inhibiting glutathione synthesis | |
| 7821 | ML 162 |
| Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4) | |
| 6429 | ML 210 |
| Induces ferroptosis in tumor initiation cells; glutathione peroxidase inhibitor | |
| 6118 | 1S,3R-RSL3 |
| Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4) | |
| 1965 | Simvastatin |
| Induces ferroptosis; AMPK activator; also HMG-CoA reductase inhibitor | |
| 6814 | Sorafenib |
| Induces ferroptosis; also Raf-1, VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT inhibitor | |
| 4935 | Sulfasalazine |
| Ferroptosis inducer; cystine-glutamate antiporter inhibitor and inhibitor of NF-κB activation |
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