Ferroptosis Activators

Cat. No. Product Name / Activity
5449 Erastin
Ferroptosis activator; also mitochondrial VDAC modulator
6280 FIN 56
Ferroptosis activator
0218 L-Glutamic acid
Induces ferroptosis; endogenous, non-selective agonist
6954 L-Buthionine sulfoximine
Induces ferroptosis by inhibiting glutathione synthesis
6429 ML 210
Induces ferroptosis in tumor initiation cells; glutathione peroxidase inhibitor
6118 1S,3R-RSL3
Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4)
1965 Simvastatin
Induces ferroptosis; also HMG-CoA reductase inhibitor
6814 Sorafenib
Induces ferroptosis; also Raf-1, VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT inhibitor
4935 Sulfasalazine
Ferroptosis inducer; cystine-glutamate antiporter inhibitor and inhibitor of NF-κB activation