MEK Inhibitors
| Cat. No. | Product Name / Activity |
|---|---|
| 1777 | Arctigenin |
| Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation | |
| 4842 | BIX 02189 |
| Selective MEK5 and ERK5 inhibitor | |
| 4192 | PD 0325901 |
| Potent inhibitor of MEK1/2 | |
| 4237 | PD 184352 |
| Selective MEK inhibitor | |
| 2605 | PD 198306 |
| Selective inhibitor of MEK1/2 | |
| 4824 | PD 334581 |
| MEK1 inhibitor | |
| 1213 | PD 98059 |
| MEK inhibitor | |
| 1969 | SL 327 |
| Selective inhibitor of MEK1 and MEK2; brain penetrant | |
| 7709 | Trametinib |
| Potent and selective MEK inhibitor; orally bioavailable | |
| 1144 | U0126 |
| Potent, selective inhibitor of MEK1 and 2 |
MAPK Signaling Review
Our MAPK signaling review gives an overview of the MAPK signaling cascade and summarizes small molecule inhibitors of the pathway.
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