GIP Receptor

The GIP (gastric inhibitory polypeptide or glucose-dependent insulinotropic peptide) receptor is a member of the glucagon receptor family that also includes glucagon, GLP-1, GLP-2, secretin and GHRH receptors. The GIP receptor is involved in glucose homeostasis.

Products
Background
Literature (3)
Gene Data

GIP Receptor Agonists

Cat. No. Product Name / Activity
2257 GIP (1-39)
Highly potent insulinotropic peptide; GIP agonist
2084 GIP (human)
Potent insulinotropic gut hormone; GIP agonist
6699 [D-Ala2]-GIP (human)
Highly potent GIP agonist

GIP Receptor Antagonists

Cat. No. Product Name / Activity
5838 [Pro3]-GIP (Mouse)
GIP receptor antagonist

The GIP (gastric inhibitory polypeptide or glucose-dependent insulinotropic peptide) receptor is a member of the glucagon receptor family that also includes glucagon, GLP-1, GLP-2, secretin and GHRH receptors. The GIP receptor is involved in glucose homeostasis via potentiation of glucose-dependent insulin secretion from the pancreatic islet β-cells. It also inhibits gastric acid secretion. The tissue distribution of this receptor is broad, with high levels of expression in the islet β-cells. The human GIP receptor gene is localized on chromosome 19q13.3.

External sources of pharmacological information for GIP Receptor :

Literature for GIP Receptor

Tocris offers the following scientific literature for GIP Receptor to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


GPCR Product Listing

GPCR Product Listing

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Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
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Peptides Involved in Appetite Modulation Scientific Review

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.

GIP Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human GIPR NM_000164 P48546
Mouse Gipr NM_001080815 Q0P543
Rat Gipr NM_012714 P43219