Glucagon Receptors
The glucagon receptor is a member of the glucagon receptor family that also includes GLP-1, GLP-2, secretin, GHRH and GIP receptors. The glucagon receptor regulates blood glucose levels and is predominantly expressed in the pancreas, liver and kidneys.
Glucagon Receptor Agonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 6927 | Glucagon (Human, Porcine) |
| Endogenous glucagon receptor agonist | |
Glucagon Receptor Antagonists |
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| Cat. No. | Product Name / Activity |
| 2216 | des-His1-[Glu9]-Glucagon (1-29) amide |
| Glucagon receptor antagonist | |
| 2311 | L-168,049 |
| Potent, orally active human glucagon receptor antagonist | |
Glucagon Receptor Modulators |
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| Cat. No. | Product Name / Activity |
| 6807 | NNC 0640 |
| Negative allosteric modulator of glucagon and GLP-1 receptors | |
Other |
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| Cat. No. | Product Name / Activity |
| 2094 | Oxyntomodulin (porcine, bovine) |
| Endogenous gut peptide; modulates feeding and metabolism | |
The glucagon receptor is a member of the glucagon receptor family that also includes GLP-1, GLP-2, secretin, GHRH and GIP receptors. The glucagon receptor regulates blood glucose levels via control of hepatic glycogenolysis and gluconeogenesis, and via regulation of insulin release from the β-cells of pancreatic islets.
The glucagon receptor is predominantly expressed in the pancreas, liver and kidneys, but is also found to a lesser extent in the heart, adipose tissue, spleen, thymus and adrenal glands. The human glucagon receptor gene is localized on chromosome 17q25.
External sources of pharmacological information for Glucagon Receptors :
Literature for Glucagon Receptors
Tocris offers the following scientific literature for Glucagon Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Our Peptides Involved in Appetite Modulation review gives an overview of the peptides implicated in appetite regulation and energy homeostasis.
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