Glucagon-Like Peptide 2 Receptors

Glucagon-like peptide 2 (GLP-2) receptors are members of the glucagon receptor family that also includes glucagon, GLP-1, secretin, GHRH and GIP receptors. GLP-2 receptors are found in the CNS and the gastrointestinal system, with the highest expression levels in the jejunum.

Products
Background
Literature
Gene Data
Cat No Product Name / Activity
2258 GLP-2 (human)
Endogenous hormone; displays intestinotrophic activity
2259 GLP-2 (rat)
Endogenous hormone; displays intestinotrophic activity

Glucagon-like peptide 2 (GLP-2) receptors are members of the glucagon receptor family that also includes glucagon, GLP-1, secretin, GHRH and GIP receptors. GLP-2 receptors are found in the central nervous system and the gastrointestinal system, with the highest expression levels in the jejunum.

The principle role of GLP-2 receptors appears to be the maintenance of the growth and absorptive function of the intestinal mucosal villus epithelium and they have also been implicated in nutrient absorption. The human GLP-2 receptor gene is localized on chromosome 17p13.3.

External sources of pharmacological information for Glucagon-Like Peptide 2 Receptors :

Literature for Glucagon-Like Peptide 2 Receptors

GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
Peptide Hormone Receptors

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

  • Anterior Pituitary Regulation
  • Blood Pressure Regulation
  • Feeding and Appetite Regulation
  • Glucose Regulation
  • Peptide Hormone Processing
Peptides Involved in Appetite Modulation

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.

Glucagon-Like Peptide 2 Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human GLP2R NM_004246 O95838
Mouse Glp2r NM_175681 Q5IXF8
Rat Glp2r NM_021848 Q924C8