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Secretin Receptors

Secretin receptors are members of the glucagon receptor family that also includes glucagon, GLP-1, GLP-2, GHRH and GIP receptors. Secretin receptors are classically localized to the epithelial cells within the pancreatic and biliary ducts, where they bind to the hormone secretin.

Products
Background
Literature (3)
Gene Data

Secretin Receptor Agonists
Cat. No. Product Name / Activity
1918 Secretin (human)
Gastrointestinal peptide
1919 Secretin (rat)
Gastrointestinal peptide

Related Targets

Secretin receptors are members of the glucagon receptor family that also includes glucagon, GLP-1, GLP-2, GHRH and GIP receptors. Secretin receptors are classically localized to the epithelial cells within the pancreatic and biliary ducts, where they stimulate the release of alkaline bicarbonate-rich fluid to neutralize acidic chyme from the stomach. This protects the duodenal mucosa and provides an optimal intraluminal environment for digestion to take place.

Secretin receptors are also found in the CNS, where they are thought to play a role in the regulation of the hypothalamic-pituitary-axis (HPA) axis. The human secretin receptor gene is localized on chromosome 2p14.1.

External sources of pharmacological information for Secretin Receptors :

Literature for Secretin Receptors

Tocris offers the following scientific literature for Secretin Receptors to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

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Secretin Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human SCTR NM_002980 P47872
Mouse Sctr NM_001012322 Q5FWI2
Rat Sctr NM_031115 P23811