CB2 Receptors
The CB2 receptor, also known as the peripheral cannabinoid receptor, is a member of the cannabinoid receptor group of G-protein-coupled receptors that also includes CB1 and GPR55. CB2 receptors are located primarily in immune cells both within and outside the CNS.
CB2 Receptor Agonists |
|
|---|---|
| Cat. No. | Product Name / Activity |
| 2663 | CB 65 |
| High affinity, selective CB2 agonist | |
| 3088 | HU 308 |
| Potent and selective CB2 agonist | |
| 1343 | JWH 133 |
| Potent and selective CB2 agonist | |
| 5826 | LEI 101 hydrochloride |
| Potent and selective CB2 partial agonist; orally biovailable | |
CB2 Receptor Inverse Agonists |
|
| Cat. No. | Product Name / Activity |
| 1120 | AM 630 |
| Selective CB2 inverse agonist | |
| 4756 | COR 170 |
| Selective CB2 receptor inverse agonist | |
| 2764 | GP 1a |
| CB2 receptor inverse agonist | |
| 2479 | JTE 907 |
| Selective CB2 receptor inverse agonist | |
| 5815 | SCH 336 |
| Highly potent and selective CB2 inverse agonist | |
| 5039 | SR 144528 |
| High affinity and selective CB2 inverse agonist | |
CB2 Receptor Modulators |
|
| Cat. No. | Product Name / Activity |
| 6832 | Ec2la |
| Positive allosteric modulator of CB2 receptors; active in vivo | |
The CB2 receptor, also known as the peripheral cannabinoid receptor, is a member of the cannabinoid receptor group of G-protein-coupled receptors that also includes CB1 and GPR55. CB2 receptors are located primarily in immune cells both within and outside the central nervous system. The function of these receptors includes modulation of cytokine release and immune cell migration. In the brain CB2 receptors are expressed by microglia, blood vessels and some neurons.
External sources of pharmacological information for CB2 Receptors :
Literature for CB2 Receptors
Tocris offers the following scientific literature for CB2 Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Pain Research Product Guide
A collection of over 280 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.
Epilepsy Poster
Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.
Our Pain guide highlights over 280 products for Pain research.
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Our Cannabinoid review gives an overview of the pharmacological ligands used to study the cannabinoid CB1 and CB2 receptors.
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Written by Alsa Pitkänen and Xavier Ekolle Ndode-Ekane, this poster summarizes current knowledge about how epilepsy develops.
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