CB2 Receptors
The CB2 receptor, also known as the peripheral cannabinoid receptor, is a member of the cannabinoid receptor group of G-protein-coupled receptors that also includes CB1 and GPR55. CB2 receptors are located primarily in immune cells both within and outside the CNS.
CB2 Receptor Agonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 2663 | CB 65 |
| High affinity, selective CB2 agonist | |
| 3088 | HU 308 |
| Potent and selective CB2 agonist | |
| 1343 | JWH 133 |
| Potent and selective CB2 agonist | |
| 5826 | LEI 101 hydrochloride |
| Potent and selective CB2 partial agonist; orally biovailable | |
CB2 Receptor Inverse Agonists |
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| Cat. No. | Product Name / Activity |
| 1120 | AM 630 |
| Selective CB2 inverse agonist | |
| 4756 | COR 170 |
| Selective CB2 receptor inverse agonist | |
| 2764 | GP 1a |
| CB2 receptor inverse agonist | |
| 2479 | JTE 907 |
| Selective CB2 receptor inverse agonist | |
| 5815 | SCH 336 |
| Highly potent and selective CB2 inverse agonist | |
| 5039 | SR 144528 |
| High affinity and selective CB2 inverse agonist | |
CB2 Receptor Modulators |
|
| Cat. No. | Product Name / Activity |
| 6832 | Ec2la |
| Positive allosteric modulator of CB2 receptors; active in vivo | |
The CB2 receptor, also known as the peripheral cannabinoid receptor, is a member of the cannabinoid receptor group of G-protein-coupled receptors that also includes CB1 and GPR55. CB2 receptors are located primarily in immune cells both within and outside the central nervous system. The function of these receptors includes modulation of cytokine release and immune cell migration. In the brain CB2 receptors are expressed by microglia, blood vessels and some neurons.
External sources of pharmacological information for CB2 Receptors :
Literature for CB2 Receptors
Tocris offers the following scientific literature for CB2 Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.
Our Cannabinoid review gives an overview of the pharmacological ligands used to study the cannabinoid CB1 and CB2 receptors.
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