The CB1 receptor, also known as the central cannabinoid receptor, is a member of the cannabinoid receptor group of G-protein-coupled receptors that also includes CB2 and GPR55. CB1 receptors are found mainly in the terminals of central and peripheral neurons.
CB1 Receptor Agonists |
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Cat. No. | Product Name / Activity |
1319 | ACEA |
Potent and highly selective CB1 agonist | |
0878 | Oleamide |
CB1 agonist | |
CB1 Receptor Inverse Agonists |
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Cat. No. | Product Name / Activity |
1115 | AM 281 |
Potent and selective CB1 inverse agonist | |
3791 | Hemopressin (human, mouse) |
Selective CB1 inverse agonist | |
2387 | LY 320135 |
Selective CB1 inverse agonist | |
0923 | SR 141716A |
Selective CB1 inverse agonist | |
7131 | TM 38837 |
Highly potent CB1 inverse agonist; peripherally restricted | |
CB1 Receptor Antagonists |
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Cat. No. | Product Name / Activity |
1117 | AM 251 |
Potent CB1 antagonist; also GPR55 agonist | |
6193 | AM 4113 |
High affinity and selective CB1 antagonist | |
5443 | AM 6545 |
High affinity and selective CB1 antagonist | |
6763 | AVE 1625 |
Potent and selective CB1 receptor antagonist | |
4236 | CP 945598 hydrochloride |
CB1 antagonist | |
5746 | NESS 0327 |
Ultra-high affinity and selective CB1 antagonist | |
CB1 Receptor Modulators |
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Cat. No. | Product Name / Activity |
2957 | Org 27569 |
Potent allosteric modulator of CB1 receptors | |
5321 | PSNCBAM-1 |
Negative allosteric modulator of CB1 receptors | |
Other |
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Cat. No. | Product Name / Activity |
2540 | Tocrifluor T1117 |
Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117) |
The CB1 receptor, also known as the central cannabinoid receptor, is a member of the cannabinoid receptor group of G-protein-coupled receptors that also includes CB2 and GPR55. CB1 receptors are found mainly in the terminals of central and peripheral neurons, where they usually mediate inhibition of neurotransmitter release. They can also be present on some non-neuronal cells, including immune cells.
Tocris offers the following scientific literature for CB1 Receptors to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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