Adrenergic β2 Receptors
The adrenergic β2 receptor (β2-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes α1A, α1B, α1D, α2A, α2B, α2C, β1 and β3. They are located primarily in the CNS, heart, kidney and muscle.
Agonists |
|
|---|---|
| Cat No | Product Name / Activity |
| 6219 | Arformoterol tartrate |
| Long-acting β2 agonist (LABA) | |
| 1448 | Formoterol hemifumarate |
| Potent and selective β2 agonist | |
| 1102 | Procaterol hydrochloride |
| Potent β2 agonist | |
| 0634 | Salbutamol hemisulfate |
| β agonist (β2 > β1) | |
| 4712 | Salmeterol xinafoate |
| Long-acting β2 agonist; bronchodilator | |
| 1051 | Zinterol hydrochloride |
| Selective β2 agonist | |
Antagonists |
|
| Cat No | Product Name / Activity |
| 0821 | ICI 118,551 hydrochloride |
| Very selective β2 antagonist/inverse agonist | |
Ligand-sets |
|
| Cat No | Product Name / Activity |
| 1873 | β-Adrenoceptor Agonist Tocriset™ |
| Selection of 3 β-adrenoceptor agonists (Cat. Nos. 0948, 1747 and 1660) | |
| 1874 | β-Adrenoceptor Antagonist Tocriset™ |
| Selection of 3 β-adrenoceptor antagonists (Cat. Nos. 1024, 0821 and 1511) | |
The adrenergic β2 receptor (β2-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes α1A, α1B, α1D, α2A, α2B, α2C, β1 and β3. They are located primarily in the CNS, heart, kidney and muscle where they are involved in smooth muscle relaxation (e.g. bronchodilation). The human adrenergic β2 receptor gene has been localized to chromosome 5 (5q31-q32)
External sources of pharmacological information for Adrenergic β2 Receptors :
Literature for Adrenergic β2 Receptors
Cardiovascular Research Product Guide
A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:
- Hypertension
- Thrombosis and Hemostasis
- Atherosclerosis
- Myocardial Infarction
- Ischemia/Reperfusion Injury
- Arrhythmias
- Heart Failure
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Secretin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Asthma Poster
Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.
Cardiovascular Poster
Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Our Cardiovascular Guide highlights over 250 products for cardiovascular research.
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Written by Peter J. Barnes
Our Asthma poster highlights key pathways and new therapies used to treat asthma, including those currently in clinical development.
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Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity.
Request copyDownload PDFWritten by P. Skolnich et al
Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder.
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