CRISPR Reagents

Essential tools for life science research

More Information »CRISPR is a technology for the targeted editing and regulation of genes that can be applied to a number of biological systems. Tocris offers small molecules that can enhance the efficiency of the CRISPR-mediated gene editing process.

CRISPR Reagents

Product Name / Activity
4150 Azidothymidine
Decreases CRISPR-mediated HDR efficiency
1231 Brefeldin A
Enhances CRISPR-mediated HDR efficiency
3412 (Z)-4-Hydroxytamoxifen
Activates intein-linked inactive Cas9, reducing off-target CRISPR-mediated gene editing
4840 KU 0060648
Enhances HDR efficiency and attenuates NHEJ frequency
2197 L-755,507
Enhances CRISPR-mediated HDR efficiency
5054 ME 0328
Enhances CRISPR-Cas9-mediated HER2 mutation frequency; PARP3 inhibitor
1228 Nocodazole
Enhances HDR efficiency; also increases Cas9-mediated gene editing frequencies
3712 NU 7441
Enhances HDR efficiency and attenuates NHEJ frequency
5810 RS 1
Enhances HDR efficiency and increases CRISPR-mediated knock-in efficiencies
5342 SCR7 pyrazine
Enhances HDR efficiency

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New Product Guide

Spring/Summer 2017

New Product Guide (Spring/Summer 2017)

Our New Product guide highlights over 130 new products added in the first half of 2017. View PDF today.

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