Transient Receptor Potential Channels

Transient receptor potential (TRP) channels are a superfamily of cation channels that are currently divided into six families. TRP channels are expressed ubiquitously and are activated by a wide range of stimuli.

Transient Receptor Potential Channel Target Files

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TRP subunits assemble into homo- or heterotetramers with varied permeation properties. They are often functionally associated with G-protein-coupled receptors, receptor tyrosine kinases and phospholipase C and are regulated by the multipotent phosphatidylinositol pathway. Since TRPs are intimately linked with intracellular Ca2+ signaling, they are implicated in the control of cell cycle progression, cell migration, apoptosis and epithelial uptake of divalent ions.

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Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

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Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Life Science Poster

Our Peripheral Sensitization poster gives a summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request copy or view PDF today.

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