The ankyrin-like receptor family (TRPA1) is a member of the transient receptor potential (TRP) superfamily of ion channels. TRPA1 is classed as a thermoTRP: a TRP channel which is gated by temperature and functions as a temperature transducer.
TRPA1 Activators |
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Cat. No. | Product Name / Activity |
5178 | ASP 7663 |
Selective TRPA1 activator | |
1531 | Icilin |
Activates a novel cold receptor. Cooling agent | |
6269 | JT010 |
Potent and selective TRPA1 channel activator | |
4901 | Optovin |
Reversible photoactive TRPA1 activator | |
3197 | Polygodial |
TRPA1 channel activator; analgesic and antifungal | |
1418 | Resveratrol |
TRPA1 activator: also cyclooxygenase inhibitor | |
TRPA1 Blockers |
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Cat. No. | Product Name / Activity |
4716 | A 967079 |
Selective TRPA1 channel blocker | |
5914 | AM 0902 |
Potent and selective TRPA1 antagonist | |
3296 | AP 18 |
Reversible TRPA1 channel blocker | |
2896 | HC 030031 |
Selective TRPA1 blocker | |
3938 | TCS 5861528 |
TRPA1 blocker |
The ankyrin-like receptor family (TRPA1) is a member of the transient receptor potential (TRP) superfamily of ion channels. TRPA1 is classed as a thermoTRP: a TRP channel which is gated by temperature and functions as a temperature transducer. This channel is thought to be indirectly activated by cold; it is often expressed in the same neurons as TRPV1, another thermoTRP, which senses heat.
TRPA1 is sensitive to numerous chemical irritants including cinnamaldehyde, allicin and eugenol. The receptor has been linked to nociceptive transduction and neurogenic inflammation.