Mesenchymal Stem Cells

Mesenchymal Stem Cells (MSCs) are a heterogeneous subset of stromal stem cells that originate from the mesoderm layer of the fetus. They can differentiate into cells of the mesodermal lineage, such as adipocytes, and osteocytes.

Products
Literature
Cat No Product Name / Activity
2840 AICAR
AMPK activator; promotes osteogenic differentiation of bone marrow-derived MSCs
3842 5-Azacytidine
DNA methyltransferase inhibitor; induces differentiation of MSCs into cardiomyocytes
1126 Dexamethasone
Anti-inflammatory glucocorticoid; induces differentiation of human MSCs
4918 GSA 10
Smo receptor agonist; induces differentiation of mesenchymal progenitor cells into osteoblasts
4513 Kartogenin
Potently induces chondrogenesis in MSCs
5552 Liothyronine sodium
Promotes adipogenic differentiation of MSCs; thyroid hormone (T3) analog
4106 Nicotinamide
Promotes MSC differentiation; anti-inflammatory agent
5778 2-Phospho-L-ascorbic acid trisodium salt
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
4551 Purmorphamine
Smo receptor agonist; induces differentiation of mesenchymal progenitor cells into osteoblasts
6187 SK 216
Attenuates TGF-β-dependent epithelial-mesenchymal transition; Also PAI-1 inhibitor
1496 SP 600125
JNK inhibitor; prevents BMP9-induced osteogenic differentiation of MSCs
4749 Strontium chloride
Calcium sensing receptor (CaSR) agonist; induces osteogenic differentiation of MSCs
3877 TCS 2210
Inducer of neuronal differentiation in MSCs
2293 Zebularine
DNA methyltransferase inhibitor; induces cardiomyocyte differentiation in MSCs

Literature for Mesenchymal Stem Cells

Tocris offers the following scientific literature for Mesenchymal Stem Cells to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Stem Cells

Stem Cells Scientific Review

Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.

Stem Cells

Stem Cells Poster

Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.