New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat. No. Product Name / Activity Date Added
7579 Olaparib Jan 2022
Potent PARP inhibitor
7457 CAM 833 Jan 2022
Selective orthosteric inhibitor of the BRCA2-RAD51 interaction
7578 Tocriscreen Epigenetics 3.0 Jan 2022
A library of 101 epigenetic compounds (250 μL, 10 mM DMSO solutions) for high throughput screening, high content screening and chemical biology applications
7206 5-Ethynyluridine Jan 2022
Uridine analog, used for labeling RNA synthesis
7497 Vandetanib Jan 2022
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
7541 Helianorphin-19 Jan 2022
Opioid receptor (KOR) agonist
7549 BAY 1816032 Jan 2022
Potent and selective BUB1 kinase inhibitor
6955 Ceapin A7 Jan 2022
Selective inhibitor of ATF6α; sensitizes cells to ER stress
7466 BI dihydrochloride Jan 2022
DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers
7551 NCT 02 Dec 2021
Molecular glue; induces degradation of CCNK and CDK12
7504 MD15 Dec 2021
Negative control for MD13 (Cat. No. 7503)
7575 aTAG 2139-NEG Dec 2021
Negative control for aTAG 2139 (Cat. no. 6970)
7566 VH 032 amide-alkylC9-amine Dec 2021
VHL ligand with alkyl linker and terminal amine for onward chemistry
7568 VH 032 amide-PEG6-amine Dec 2021
VHL ligand with PEG linker and terminal amine for onward chemistry
7478 Lyophilized OneStep RT-qPCR Master Mix Dec 2021
Lyophilized OneStep RT-qPCR Master Mix
7477 Lyophilized qPCR Master Mix Dec 2021
Lyophilized qPCR Master Mix
7405 TWS 119 Dec 2021
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation
7527 TSA Vivid Fluorophore Kit 650 Nov 2021
Signal amplification kit for use in ISH, ICC and IHC
7526 TSA Vivid Fluorophore Kit 570 Nov 2021
Signal amplification kit for use in ISH, ICC and IHC
7523 TSA Vivid Fluorophore Kit 520 Nov 2021
Signal amplification kit for use in ISH, ICC and IHC
7503 MD13 Nov 2021
Potent MIF Degrader (PROTAC®)
4340 TAK 779 Nov 2021
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
TB4703-RMU DZNep HCl Nov 2021
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
6718 ±-MF 094 Nov 2021
Selective USP30 inhibitor
6965 CGI 1746 Nov 2021
Potent, reversible BTK inhibitor
7474 EN6 Nov 2021
H+ ATPase activator; activates autophagy; inactivates mTORC1 signaling
TB4489-RMU DBZ Nov 2021
DBZ synthesized to Ancillary Material Grade
7515 Lenalidomide 4'-PEG3-azide Nov 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7509 NR12S Nov 2021
Fluorogenic lipid membrane dye
7310 Emricasan Nov 2021
Potent pan-caspase inhibitor
6979 SEN 177 Nov 2021
Potent glutaminyl cyclase inhibitor; disrupts binding of SIRP-α to CD47
7433 cis-SIM1 Nov 2021
Negative control for SIM1 (Cat. No. 7432)
7454 Cediranib Oct 2021
Potent inhibitor of VEGFR, PDGFR and FGFR
7337 Cysmethynil Oct 2021
ICMT inhibitor; arrests cell-cycle at G1 phase
7508 EMD 527040 hydrochloride Oct 2021
ανβ6 integrin inhibitor
3786 Celecoxib Oct 2021
Selective cyclooxygenase-2 (COX-2) inhibitor
3784 Sildenafil citrate Oct 2021
Potent PDE5 inhibitor; orally active
7379 CB 5083 Oct 2021
Potent p97 ATPase inhibitor
7521 Thalidomide 4'-ether-alkylC3-azide Oct 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7516 Lenalidomide 4'-alkylC3-azide Oct 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7410 PARPYnD Oct 2021
PARP inhibitor; photoaffinity probe
7520 Thalidomide 4'-ether-PEG3-azide Oct 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7424 EMI 48 Oct 2021
Inhibitor of EGFR mutants
7518 Thalidomide 4'-ether-PEG1-azide Oct 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7513 Lenalidomide 4'-PEG1-azide Oct 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7473 Lenalidomide 5'-piperazine-4-methylpiperidine Oct 2021
Cereblon ligand with terminal piperidine for onward chemistry
7472 Lenalidomide 5'-piperazine Oct 2021
Cereblon ligand with terminal piperazine for onward chemistry
7445 GPR52 Comp-43 Oct 2021
GPR52 receptor antagonist
7522 Thalidomide 4'-ether-alkylC5-azide Oct 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7519 Thalidomide 4'-ether-PEG2-azide Oct 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7517 Lenalidomide 4'-alkylC5-azide Oct 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7514 Lenalidomide 4'-PEG2-azide Oct 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7431 Cyanine 5.5, SE Oct 2021
Far red fluorescent dye for the labeling of amines; supplied as NHS ester
7341 STX 64 Oct 2021
Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II
7086 StemRegenin 1 Sep 2021
Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
7242 Ac-FLTD-CMK Sep 2021
Potent and selective inhibitor of caspases 1, 5 and 4
7458 iBET-BD2 Sep 2021
Potent and selective pan-BD2 inhibitor; orally bioavailable
7489 TCH-165 Sep 2021
Enhancer of 20S proteasome assembly and 20S-mediated protein degradation
7305 Defactinib Sep 2021
Potent and selective FAK and Pyk2 inhibitor
6141 BI-6901 Sep 2021
Potent and selective CCR10 antagonist
6498 TASP 0277308 Sep 2021
Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
6687 1R,3R-RSL3 Sep 2021
Negative control for 1S,3R-RSL3 (Cat. No. 6118)
6804 Hoechst Janelia Fluor® 646 Sep 2021
Fluorogenic, red-emitting DNA probe
7321 Pritelivir Sep 2021
Potent and selective herpes simplex virus (HSV) helicase primase inhibitor
TB1099-RMU Forskolin Sep 2021
Forskolin synthesized to Ancillary Material Grade
7304 JH-XI-10-02 Sep 2021
CDK8 Degrader (PROTAC®)
7057 VU 0071063 Sep 2021
Selective activator of SUR1 Kir6.2 channels
7460 SGC SMARCA-BRDVIII Sep 2021
Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor
7450 SGC CK2-1 Sep 2021
Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2
4894 ML 299 Sep 2021
Potent inhibitor of PLD1 and PLD2; CNS penetrant
5114 K34c Sep 2021
Potent and selective α5β1 integrin inhibitor
7406 Rf470DL Sep 2021
Blue rotor-fluorogenic fluorescent D-amino acid for labeling peptidoglycans in live bacteria
7214 VH 032 amide-PEG2-acid Sep 2021
VHL ligand with PEG linker and terminal acid for onward chemistry
7373 FNIR-Tag, NHS Sep 2021
Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester
7432 SIM1 Sep 2021
Potent and selective trivalent BET Bromodomain Degrader (PROTAC®)
6862 Psoralen-triethylene glycol azide Sep 2021
RNA conformation probe; reagent for COMRADES RNA platform
7139 CeMMEC1 Sep 2021
TAF1 inhibitor
7309 Vemurafenib Sep 2021
Potent BRAF and CRAF inhibitor
7157 YKL 5-124 Sep 2021
Potent and selective CDK7 inhibitor; induces cell cycle arrest
7421 LC 2 Epimer Sep 2021
Negative control for LC 2 (Cat. No. 7420)
7408 OGDA Sep 2021
Green fluorescent D-amino acid; compatible with STED microscopy
7486 Roxadustat Aug 2021
HIF-PH inhibitor; erythropoietic
TB6053-RMU LDN 193189 Aug 2021
LDN 193189 synthesized to Ancillary Material Grade
TB3000-RMU Gefitinib Aug 2021
Iressa synthesized to Ancillary Material Grade
TB0760-RMU AM 580 Aug 2021
AM 580 synthesized to Ancillary Material Grade
TB5758-RMU AGN 193109 Aug 2021
AGN 193109 synthesized to Ancillary Material Grade
7371 Neratinib Aug 2021
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
7425 CG 428 Aug 2021
Potent tropomyosin receptor kinase (TRK) degrader
6497 GSK 2833503A Aug 2021
Potent and selective TRPC6 and TRPC3 antagonist
7426 CG 428-Neg Aug 2021
Negative control for CG 428 (Cat. No. 7425)
7194 Erlotinib Hydrochloride Aug 2021
Potent, reversible EGFR tyrosine kinase inhibitor
7320 Methoxyluteolin Aug 2021
Inhibitor of pro-inflammatory mediator release from mast cells
7375 RO 8191 Aug 2021
IFNα receptor 2 agonist
7419 Kyoto Probe-1 Aug 2021
Fluorescent probe that selectively identifies undifferentiated iPS/ES cells
7420 LC 2 Aug 2021
Selective KRAS PROTAC®
3345 MLN 4760 Aug 2021
Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor
7469 Pomalidomide 5'-piperazine-4-methylpiperidine Jul 2021
Cereblon ligand with terminal piperidine for onward chemistry
7462 ET 18-OCH3 Jul 2021
Selective PI-PLC inhibitor, also PAF receptor agonist
6977 Bobcat339 Jul 2021
Ten-eleven translocation methylcytosine dioxygenase (TET) inhibitor
4327 JW 480 Jul 2021
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)