Oxytocin Receptors
Oxytocin receptors (OT) are G-protein-coupled receptors that mediate parturition and lactation. They are closely related to vasopressin receptors. Oxytocin receptors are coupled to Gq/11 proteins and are localized to the myoepithelial cells of the mammary gland.
Oxytocin Receptor Agonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 4852 | Carbetocin |
| Oxytocin analog | |
| 1910 | Oxytocin |
| Involved in uterine contraction and lactation | |
| 4625 | TC OT 39 |
| Potent non-peptide oxytocin receptor partial agonist; also V1a receptor antagonist | |
| 3933 | WAY 267464 dihydrochloride |
| Potent non-peptide oxytocin receptor agonist | |
Oxytocin Receptor Antagonists |
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| Cat. No. | Product Name / Activity |
| 6332 | Atosiban |
| Potent oxytocin receptor antagonist | |
| 2641 | L-368,899 hydrochloride |
| Potent, non-peptide oxytocin receptor antagonist | |
| 2410 | L-371,257 |
| Potent and selective oxytocin receptor antagonist | |
Oxytocin receptors (OT) are G-protein-coupled receptors that mediate parturition and lactation. They are closely related to vasopressin receptors. Oxytocin receptors are coupled to Gq/11 proteins and are localized to the myoepithelial cells of the mammary gland, and are also expressed in the myometrium and endometrium of the uterus at the end of pregnancy.
Oxytocin receptors are involved in smooth muscle contraction of the uterus during parturition and facilitate lactation. These receptors are widespread throughout the central nervous system and modulate a variety of behaviors. These include responses to stress and anxiety, social memory and recognition, bonding, and sexual and maternal behaviors. Antinociceptive effects of oxytocin have also been observed in experimental models. The human gene encoding the oxytocin receptor is localized to chromosome 3p25.
External sources of pharmacological information for Oxytocin Receptors :
Literature for Oxytocin Receptors
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GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Peptide Hormone Receptors Product Listing
A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:
- Anterior Pituitary Regulation
- Blood Pressure Regulation
- Feeding and Appetite Regulation
- Glucose Regulation
- Peptide Hormone Processing
Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors.
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