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WAY 267464 dihydrochloride
Potent, selective non-peptide oxytocin receptor (OTR) agonist (Ki = 58.4 nM at human OTR). Exhibits anxiolytic-like effects. May have therapeutic potential for the treatment of psychosis and schizophrenia.
Sold for research purposes under agreement from Pfizer Inc.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 654.59. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.8 mM||1.91 mL||9.55 mL||19.1 mL|
|4 mM||0.38 mL||1.91 mL||3.82 mL|
|8 mM||0.19 mL||0.95 mL||1.91 mL|
|40 mM||0.04 mL||0.19 mL||0.38 mL|
References are publications that support the biological activity of the product.
Ring et al (2010) Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxyt. receptor agonist. Neuropharmacology 58 6 PMID: 19615387
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Keywords: WAY 267464 dihydrochloride, WAY 267464 dihydrochloride supplier, WAY267464, dihydrochloride, oxytocin, agonists, OT, receptors, non-peptide, pfizer, Oxytocin, Receptors, 3933, Tocris Bioscience
2 Citations for WAY 267464 dihydrochloride
Citations are publications that use Tocris products. Selected citations for WAY 267464 dihydrochloride include:
Huo et al (2018) Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala. PLoS One 13 e0193395 PMID: 29470551
Xiao et al (2017) Biased OXTergic Modulation of Midbrain DA Systems. Neuron 95 368 PMID: 28669546
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Literature in this Area
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