Nicotinic Receptors (Non-selective)

Agonists

Cat. No. Product Name / Activity
2809 Acetylcholine chloride
Endogenous neurotransmitter
0352 4-Acetyl-1,1-dimethylpiperazinium iodide
nAChR agonist
0351 1-Acetyl-4-methylpiperazine hydrochloride
nAChR agonist
1971 (+)-Anabasine hydrochloride
High affinity nAChR partial agonist
0789 (±)-Anatoxin A fumarate
nAChR agonist
3549 3-Bromocytisine
Potent α4β4, α4β2 and α7 nAChR agonist
2810 Carbamoylcholine chloride
Non-selective cholinergic agonist
3110 (-)-Cotinine
Major metabolite of nicotine
1390 (-)-Cytisine
Potent and selective neuronal nAChRagonist
0684 (±)-Epibatidine
High affinity nAChR agonist
1077 (-)-Lobeline hydrochloride
Nicotinic partial agonist
3546 (-)-Nicotine ditartrate
Prototypical nAChR agonist
6700 PA Nic
Caged nicotine; photoactivated by one-photon and two-photon excitation
1271 RJR 2429 dihydrochloride
nAChR agonist; displays selectivity for α4β2, α1βγδ and α3β4 subtypes
3855 RuBi-Nicotine
Caged nicotine; rapidly excitable by visible light
4766 SIB 1508Y maleate
Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptors

Antagonists

Cat. No. Product Name / Activity
0424 Benzoquinonium dibromide
nAChR antagonist
4128 Bisindolylmaleimide II
Potent nAChR antagonist; also potent PKC inhibitor
3221 bPiDDB
Orthosteric neuronal nAChR antagonist
2722 Catestatin
Non-competitive nAChR antagonist
1001 Chlorisondamine diiodide
nAChR antagonist; slow offset
4111 Hexamethonium bromide
Non-competitive nAChR antagonist
2843 Mecamylamine hydrochloride
Non-competitive nAChR antagonist
6552 PAMP-20 (human)
Noncompetitive nAChR antagonist; also MRGPRX2 agonist
0693 Pancuronium dibromide
Neuromusclar nAChR antagonist
3287 Prochlorperazine dimaleate
nAChR antagonist; also D2 and 5-HT3 antagonist
2438 TMPH hydrochloride
Neuronal nAChR antagonist
2820 (+)-Tubocurarine chloride
nAChR antagonist

Modulators

Cat. No. Product Name / Activity
0686 Galanthamine hydrobromide
Cholinesterase inhibitor; allosteric potentiator of nicotinic ACh receptors