A potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 190.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.26 mL||26.28 mL||52.57 mL|
|5 mM||1.05 mL||5.26 mL||10.51 mL|
|10 mM||0.53 mL||2.63 mL||5.26 mL|
|50 mM||0.11 mL||0.53 mL||1.05 mL|
References are publications that support the products' biological activity.
Happe et al (1994) Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H]cytisine. Neuroscience 62 929 PMID: 7870314
Papke et al (1994) Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit. Mol.Pharmacol. 45 142 PMID: 8302273
Reavill et al (1990) Behavioural and pharmacokinetic studies on nicotine, cytisine and lobeline. Neuropharmacology 29 619 PMID: 2385332
If you know of a relevant reference for (-)-Cytisine, please let us know.
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Keywords: (-)-Cytisine, supplier, Potent, selective, neuronal, nicotinic, agonists, Acetylcholine, Receptors, Non-Selective, Subtypes, nAChR, Nicotinic, Receptors, (Non-selective), Nicotinic, Receptors, (Non-selective), Tocris Bioscience
1 Citation for (-)-Cytisine
Citations are publications that use Tocris products. Selected citations for (-)-Cytisine include:
Li et al (2010) Cytisine induces autonomic cardiovascular responses via activations of different nicotinic receptors. Auton Neurosci 154 14 PMID: 19887306
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