Oxygenases/Oxidases

Oxygenases and oxidases belong to the E.C. 1 class of enzymes. Oxygenases catalyze the incorporation of oxygen into a substrate. Dioxygenases incorporate both oxygen atoms into the substrate, whilst monooxygenases incorporate a single oxygen atom as a hydroxyl group into the substrate and the second oxygen atom is reduced to water. Oxidases catalyze the transfer of two electrons from a donor to oxygen, producing hydrogen peroxide. Usually a flavin co-enzyme or metal co-factor is required.

Targets

Literature

Oxygenase/Oxidase Target Files

• Cyclooxygenases
• Heme Oxygenase
• Indoleamine 2,3 dioxygenaseNew
• Lipoxygenases

• Monoamine Oxidases
• NADPH Oxidase
• Stearoyl-CoA 9-Desaturase
• Tryptophan 2,3 dioxygenaseNew

Related Targets

• Cytochrome P450

• Other Oxygenases/Oxidases

Literature for Oxygenases/Oxidases

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